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ChemicalBook >> CAS DataBase List >> Thalidomide

Thalidomide

Thalidomide price.
  • $7 - $1767.15
  • Product name: Thalidomide
  • CAS: 50-35-1
  • MF: C13H10N2O4
  • MW: 258.23
  • EINECS:200-031-1
  • MDL Number:MFCD00153873
  • Synonyms:(+-)-THALIDOMIDE >98% IMMUNOSUPPRESSIVE, SE;N-PHTHALOLYLGLUTAMIMIDE;3-PHTHALIMIDOGLUTARIMIDE;(+/-)-THALIDOMIDE;THALIDOMIDE;(+/-)-N-(2,6-DIOXO-3-PIPERIDINYL)PHTHALIMIDE;N-(2,6-DIOXO-3-PIPERIDINYL)PHTHALIMIDE;N-(2,6-DIOXOPIPERIDIN-3-YL)PHTHALIMIDE
Price47 Properties Safety Information Description
47 prices
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Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Aronis compounds
  • AvaChem
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Iris Biotech GmbH
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
Package
  • 5MG
  • 20mg
  • 50mg
  • 100mg
  • 10mM(in 1mL DMSO)
  • 500MG
  • 1g
  • 100
  • 200mg
  • 250mg
  • 2g
  • 2.5g
  • 5g
  • 10g
  • 25g
  • 100g
  • ManufacturerAHH
  • Product numberMT-59367
  • Product descriptionThalidomide 99%
  • Packaging25g
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ90042
  • Product descriptionThalidomide
  • Packaging5g
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60271
  • Product descriptionThalidomide
  • Packaging100mg
  • Price$62.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62266
  • Product description(±)-Thalidomide 99+%
  • Packaging100mg
  • Price$102
  • Updated2023-06-20
  • Buy
  • ManufacturerAmbeed
  • Product numberA164079
  • Product description2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+%
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164079
  • Product description2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+%
  • Packaging1g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164079
  • Product description2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+%
  • Packaging5g
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164079
  • Product description2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+%
  • Packaging10g
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164079
  • Product description2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+%
  • Packaging25g
  • Price$136
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164079
  • Product description2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+%
  • Packaging100g
  • Price$449
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004382
  • Product descriptionTHALIDOMIDE 95.00%
  • Packaging5MG
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004382
  • Product descriptionTHALIDOMIDE 95.00%
  • Packaging500MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004382
  • Product descriptionTHALIDOMIDE 95.00%
  • Packaging5G
  • Price$1767.15
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4216
  • Product descriptionThalidomide
  • Packaging200mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4216
  • Product descriptionThalidomide
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS022118
  • Product description2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione ≥98%
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-59367 Thalidomide 99% 25g $310 2021-12-16 Buy
AK Scientific J90042 Thalidomide 5g $45 2021-12-16 Buy
Alfa Aesar J60271 Thalidomide 100mg $62.65 2024-03-01 Buy
Alfa Aesar J62266 (±)-Thalidomide 99+% 100mg $102 2023-06-20 Buy
Ambeed A164079 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+% 250mg $7 2021-12-16 Buy
Ambeed A164079 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+% 1g $11 2021-12-16 Buy
Ambeed A164079 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+% 5g $34 2021-12-16 Buy
Ambeed A164079 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+% 10g $63 2021-12-16 Buy
Ambeed A164079 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+% 25g $136 2021-12-16 Buy
Ambeed A164079 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+% 100g $449 2021-12-16 Buy
American Custom Chemicals Corporation API0004382 THALIDOMIDE 95.00% 5MG $550 2021-12-16 Buy
American Custom Chemicals Corporation API0004382 THALIDOMIDE 95.00% 500MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation API0004382 THALIDOMIDE 95.00% 5G $1767.15 2021-12-16 Buy
ApexBio Technology A4216 Thalidomide 200mg $55 2021-12-16 Buy
ApexBio Technology A4216 Thalidomide 10mM(in 1mL DMSO) $60 2021-12-16 Buy
Arctom AS022118 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione ≥98% 250mg $7 2021-12-16 Buy
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Properties

Melting point :269-271°C
Boiling point :401.48°C (rough estimate)
Density :1.2944 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.6 mg/mL
form :White solid
pka :10.70±0.40(Predicted)
color :white
Water Solubility :<0.1 g/100 mL at 22 ºC
λmax :300nm(lit.)
Merck :14,9255
Stability :Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey :UEJJHQNACJXSKW-UHFFFAOYSA-N
CAS DataBase Reference :50-35-1(CAS DataBase Reference)
NIST Chemistry Reference :Phthalimide, n-(2,6-dioxo-3-piperidyl)-(50-35-1)
EPA Substance Registry System :Thalidomide (50-35-1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Thalidomide was prescribed as an anti-nausea agent to help pregnant women with morning sickness in the late 1950s. It was found to be a potent teratogen, causing many different forms of birth defects and was withdrawn from the market. Thalidomide and synthetic analogs have recently been proven effective in treating inflammation associated with diseases such as leprosy, arthritis and Crohn’s disease, and in cancers such as multiple myeloma. The direct target for the teratogenicity of thalidomide was not discovered until 2010, when it was found that it interacts directly with the protein cereblon (CRBN; IC50 = 8.5 nM), a ubiquitously-expressed E3 ligase. Binding of thalidomide analogs to CRBN-DNA damage binding protein-1 complexes account for the immunomodulatory and antiproliferative effects of these compounds.

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Suppliers and manufacturers

Henan Bao Enluo International TradeCo.，LTD
Thalidomide
$10.00 /1kg
Thalidomide CAS:50-35-1
Henan Fengda Chemical Co., Ltd
Thalidomide
$1.10 /1000kg
Thalidomide CAS:50-35-1
career henan chemical co
Thalidomide
$1.00 /1kg
Thalidomide CAS:50-35-1
Shaanxi Dideu Medichem Co. Ltd
Thalidomide
$0.01 /1KG
Thalidomide CAS:50-35-1
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Hubei Jusheng Technology Co.,Ltd.
Standardpharm Co. Ltd.
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED