Thalidomide
|
- $7 - $1767.15
- Product name: Thalidomide
- CAS: 50-35-1
- MF: C13H10N2O4
- MW: 258.23
- EINECS:200-031-1
- MDL Number:MFCD00153873
- Synonyms:(+-)-THALIDOMIDE >98% IMMUNOSUPPRESSIVE, SE;N-PHTHALOLYLGLUTAMIMIDE;3-PHTHALIMIDOGLUTARIMIDE;THALIDOMIDE;(+/-)-N-(2,6-DIOXO-3-PIPERIDINYL)PHTHALIMIDE;N-(2,6-DIOXO-3-PIPERIDINYL)PHTHALIMIDE;N-(2,6-DIOXOPIPERIDIN-3-YL)PHTHALIMIDE;1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-
81 prices
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Brand
- aablocks
- ACHEMBLOCK
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Aronis compounds
- AvaChem
- Axon Medchem
- Biosynth
- BroadPharm
- Cayman Chemical
- Chem-Impex
- Crysdot
- CSNpharm
- DC Chemicals
- Iris Biotech GmbH
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 20mg
- 10mM(in1mLDMSO)
- 10mM(in 1mL DMSO)
- 5MG
- 1mg
- 100
- 100mg
- 10mM*1mLinDMSO(Solution)
- 50mg
- 200mg
- 250mg
- 500MG
- 1g
- 2g
- 2.5g
- 5g
- 10g
- 25g
- 100G
- 500g
- Manufactureraablocks
- Product numberAA006UKW
- Product descriptionN-(2,6-Dioxo-3-piperidinyl)phthalimide 98%
- Packaging1mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006UKW
- Product descriptionN-(2,6-Dioxo-3-piperidinyl)phthalimide 98%
- Packaging250mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006UKW
- Product descriptionN-(2,6-Dioxo-3-piperidinyl)phthalimide ≥98%
- Packaging1g
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006UKW
- Product descriptionN-(2,6-Dioxo-3-piperidinyl)phthalimide 98%
- Packaging5g
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006UKW
- Product descriptionN-(2,6-Dioxo-3-piperidinyl)phthalimide 98%
- Packaging10g
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006UKW
- Product descriptionN-(2,6-Dioxo-3-piperidinyl)phthalimide 98%
- Packaging25g
- Price$79
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006UKW
- Product descriptionN-(2,6-Dioxo-3-piperidinyl)phthalimide 98%
- Packaging500g
- Price$1342
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU103909
- Product description2-(2,6-Dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione 95.00%
- Packaging100G
- Price$420
- Updated2026-05-27
- Buy
- ManufacturerAHH
- Product numberMT-59367
- Product descriptionThalidomide 99%
- Packaging25g
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-59367
- Product descriptionThalidomide 97%
- Packaging25g
- Price$310
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-59367
- Product descriptionThalidomide 97%
- Packaging25g
- Price$310
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberJ90042
- Product descriptionThalidomide
- Packaging5g
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA164079
- Product description2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+%
- Packaging250mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA164079
- Product description2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+%
- Packaging1g
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA164079
- Product description2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+%
- Packaging5g
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA164079
- Product description2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+%
- Packaging10g
- Price$63
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA006UKW | N-(2,6-Dioxo-3-piperidinyl)phthalimide 98% | 1mg | $8 | 2026-05-28 | Buy |
| aablocks | AA006UKW | N-(2,6-Dioxo-3-piperidinyl)phthalimide 98% | 250mg | $10 | 2026-05-28 | Buy |
| aablocks | AA006UKW | N-(2,6-Dioxo-3-piperidinyl)phthalimide ≥98% | 1g | $16 | 2026-05-28 | Buy |
| aablocks | AA006UKW | N-(2,6-Dioxo-3-piperidinyl)phthalimide 98% | 5g | $23 | 2026-05-28 | Buy |
| aablocks | AA006UKW | N-(2,6-Dioxo-3-piperidinyl)phthalimide 98% | 10g | $36 | 2026-05-28 | Buy |
| aablocks | AA006UKW | N-(2,6-Dioxo-3-piperidinyl)phthalimide 98% | 25g | $79 | 2026-05-28 | Buy |
| aablocks | AA006UKW | N-(2,6-Dioxo-3-piperidinyl)phthalimide 98% | 500g | $1342 | 2026-05-28 | Buy |
| ACHEMBLOCK | U103909 | 2-(2,6-Dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione 95.00% | 100G | $420 | 2026-05-27 | Buy |
| AHH | MT-59367 | Thalidomide 99% | 25g | $310 | 2021-12-16 | Buy |
| AHH | MT-59367 | Thalidomide 97% | 25g | $310 | 2026-05-25 | Buy |
| AHH | MT-59367 | Thalidomide 97% | 25g | $310 | 2026-05-26 | Buy |
| AK Scientific | J90042 | Thalidomide | 5g | $45 | 2021-12-16 | Buy |
| Ambeed | A164079 | 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+% | 250mg | $7 | 2021-12-16 | Buy |
| Ambeed | A164079 | 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+% | 1g | $11 | 2021-12-16 | Buy |
| Ambeed | A164079 | 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+% | 5g | $34 | 2021-12-16 | Buy |
| Ambeed | A164079 | 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione 98+% | 10g | $63 | 2021-12-16 | Buy |
Properties
Melting point :269-271°C
Boiling point :401.48°C (rough estimate)
Density :1.2944 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.6 mg/mL
form :White solid
pka :10.70±0.40(Predicted)
color :white
Water Solubility :<0.1 g/100 mL at 22 ºC
λmax :300nm(lit.)
Merck :14,9255
Stability :Stable. Combustible. Incompatible with strong oxidizing agents.
InChI :1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)
InChIKey :UEJJHQNACJXSKW-UHFFFAOYSA-N
SMILES :O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1
CAS DataBase Reference :50-35-1(CAS DataBase Reference)
NIST Chemistry Reference :Phthalimide, n-(2,6-dioxo-3-piperidyl)-(50-35-1)
EPA Substance Registry System :Thalidomide (50-35-1)
Boiling point :401.48°C (rough estimate)
Density :1.2944 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.6 mg/mL
form :White solid
pka :10.70±0.40(Predicted)
color :white
Water Solubility :<0.1 g/100 mL at 22 ºC
λmax :300nm(lit.)
Merck :14,9255
Stability :Stable. Combustible. Incompatible with strong oxidizing agents.
InChI :1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)
InChIKey :UEJJHQNACJXSKW-UHFFFAOYSA-N
SMILES :O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1
CAS DataBase Reference :50-35-1(CAS DataBase Reference)
NIST Chemistry Reference :Phthalimide, n-(2,6-dioxo-3-piperidyl)-(50-35-1)
EPA Substance Registry System :Thalidomide (50-35-1)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Thalidomide was prescribed as an anti-nausea agent to help pregnant women with morning sickness in the late 1950s. It was found to be a potent teratogen, causing many different forms of birth defects and was withdrawn from the market. Thalidomide and synthetic analogs have recently been proven effective in treating inflammation associated with diseases such as leprosy, arthritis and Crohn’s disease, and in cancers such as multiple myeloma. The direct target for the teratogenicity of thalidomide was not discovered until 2010, when it was found that it interacts directly with the protein cereblon (CRBN; IC50 = 8.5 nM), a ubiquitously-expressed E3 ligase. Binding of thalidomide analogs to CRBN-DNA damage binding protein-1 complexes account for the immunomodulatory and antiproliferative effects of these compounds.Related product price
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