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ChemicalBook >> CAS DataBase List >> Thionine

Thionine

$40 - $456
Product name: Thionine
CAS: 581-64-6
MF: C12H10ClN3S
MW: 263.74
EINECS:209-470-3
MDL Number:MFCD00082072
Synonyms:thionin,thionine,thionine chloride,3,7-diaminophenothiazin-5-ium chloride,7-amino-3-imino-3h-phenothiazine hydrochloride,c.i. 52000;COAGULATION FACTOR FLA;FIBRINOGENASE;approx.90%dyecontent;PHENOTHIAZINE,7-AMINO-3-IMMINO-,MONOHYDROCHLORIDE;Thionin chloride,pure,certified;7-AMINO-3-IMINO-3H-PHENOTHIAZINE MONOHYDROCHLORIDE;3,7-Diaminophenothiazoniumchloride

Price6 Properties Safety Information Description

6 prices

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Brand

Cayman Chemical
Sigma-Aldrich
TRC

Package

100mg
250U
500mg
1KU
1g
150UNITS

ManufacturerCayman Chemical
Product number13188
Product descriptionThrombin (human)
Packaging250U
Price$153
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number13188
Product descriptionThrombin (human)
Packaging1KU
Price$456
Updated2024-03-01
Buy

ManufacturerSigma-Aldrich
Product numberT9326
Product descriptionThrombin human BioUltra, recombinant, expressed in HEK 293 cells, aqueous solution, ≥95% (SDS-PAGE)
Packaging150UNITS
Price$455
Updated2026-04-30
Buy

ManufacturerTRC
Product numberT367760
Product descriptionThionineChloride
Packaging1g
Price$240
Updated2021-12-16
Buy

ManufacturerTRC
Product numberT367760
Product descriptionThionineChloride
Packaging100mg
Price$40
Updated2021-12-16
Buy

ManufacturerTRC
Product numberT367760
Product descriptionThionineChloride
Packaging500mg
Price$150
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Cayman Chemical	13188	Thrombin (human)	250U	$153	2024-03-01	Buy
Cayman Chemical	13188	Thrombin (human)	1KU	$456	2024-03-01	Buy
Sigma-Aldrich	T9326	Thrombin human BioUltra, recombinant, expressed in HEK 293 cells, aqueous solution, ≥95% (SDS-PAGE)	150UNITS	$455	2026-04-30	Buy
TRC	T367760	ThionineChloride	1g	$240	2021-12-16	Buy
TRC	T367760	ThionineChloride	100mg	$40	2021-12-16	Buy
TRC	T367760	ThionineChloride	500mg	$150	2021-12-16	Buy

Properties

storage temp. :−20°C
solubility :H₂O: 1 mL/vial clear to slightly hazy, colorless solution
Colour Index :52000
form :powder
color :white
Merck :9346
Specific Activity :≥2,000units/mg protein
CAS DataBase Reference :581-64-6(CAS DataBase Reference)
EPA Substance Registry System :Thionin (581-64-6)

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H312	Harmful in contact with skin	Acute toxicity,dermal	Category 4	Warning	P280,P302+P352, P312, P322, P363,P501
H332	Harmful if inhaled	Acute toxicity,inhalation	Category 4	Warning	P261, P271, P304+P340, P312

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P322	Specific measures (see …on this label).
P330	Rinse mouth.
P363	Wash contaminated clothing before reuse.
P501	Dispose of contents/container to..…

Description

Thrombin is the last enzyme in the clotting cascade functioning to cleave fibrinogen to fibrin and potentiates the procoagulation process by activating factors V, VIII, XI, and XIII. Conversely, thrombin aids the anticoagulant process by activating protein C. Activated protein C inhibits activated factors V and VIII ultimately down-regulating further thrombin production. Thrombin is often used as a potent platelet activator in vitro. Platelet responses to thrombin are mediated through protease-activated receptors (PARs). Thrombin-mediated signaling regulates a diverse range of metabolic processes including activation of phospholipases in platelets, endothelial cells, and cardiac myocytes.

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