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ChemicalBook >> CAS DataBase List >> Tipifarnib

Tipifarnib

Tipifarnib price.
  • $28 - $2900
  • Product name: Tipifarnib
  • CAS: 192185-72-1
  • MF: C27H22Cl2N4O
  • MW: 489.4
  • EINECS:
  • MDL Number:MFCD07772347
  • Synonyms:TIPIFARNIB;TIPIFARNIB ZARNESTRA;(R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone;Zarnestra;(R)-(+)-R 115777;6-[(R)-AMino(4-chlorophenyl)(1-Methyl-1H-iMidazol-5-yl)Methyl]-4-(3-chlorophenyl)-1-Methyl-2(1H)-quinolinone;Tipifarnib(Zarnestra,NSC-702818, R-115777);IND 58359
Price47 Properties Safety Information Description
47 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5
  • 10mM(in 1mL DMSO)
  • 1unit
  • 1MG
  • 2mg
  • 25
  • 2.5mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberX1029
  • Product descriptionTipifarnib
  • Packaging10mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA412936
  • Product description(R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+%
  • Packaging2mg
  • Price$62
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA412936
  • Product description(R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+%
  • Packaging5mg
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA412936
  • Product description(R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+%
  • Packaging50mg
  • Price$361
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA412936
  • Product description(R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+%
  • Packaging10mg
  • Price$361
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA412936
  • Product description(R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+%
  • Packaging100mg
  • Price$667
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA412936
  • Product description(R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+%
  • Packaging250mg
  • Price$1270
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004807
  • Product descriptionTIPIFARNIB 0.00%
  • Packaging1MG
  • Price$440
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004807
  • Product descriptionTIPIFARNIB 0.00%
  • Packaging5MG
  • Price$551
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004807
  • Product descriptionTIPIFARNIB 0.00%
  • Packaging10MG
  • Price$647
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4227
  • Product descriptionTipifarnib(Zarnestra)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4227
  • Product descriptionTipifarnib(Zarnestra)
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4227
  • Product descriptionTipifarnib(Zarnestra)
  • Packaging10mM(in 1mL DMSO)
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4227
  • Product descriptionTipifarnib(Zarnestra)
  • Packaging25mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4227
  • Product descriptionTipifarnib(Zarnestra)
  • Packaging100mg
  • Price$960
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIFK0043
  • Product descriptionTipifarnib >98%
  • Packaging2mg
  • Price$73
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X1029 Tipifarnib 10mg $336 2021-12-16 Buy
Ambeed A412936 (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+% 2mg $62 2021-12-16 Buy
Ambeed A412936 (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+% 5mg $109 2021-12-16 Buy
Ambeed A412936 (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+% 50mg $361 2021-12-16 Buy
Ambeed A412936 (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+% 10mg $361 2021-12-16 Buy
Ambeed A412936 (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+% 100mg $667 2021-12-16 Buy
Ambeed A412936 (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one 98+% 250mg $1270 2021-12-16 Buy
American Custom Chemicals Corporation INB0004807 TIPIFARNIB 0.00% 1MG $440 2021-12-16 Buy
American Custom Chemicals Corporation INB0004807 TIPIFARNIB 0.00% 5MG $551 2021-12-16 Buy
American Custom Chemicals Corporation INB0004807 TIPIFARNIB 0.00% 10MG $647 2021-12-16 Buy
ApexBio Technology A4227 Tipifarnib(Zarnestra) 1unit $28 2021-12-16 Buy
ApexBio Technology A4227 Tipifarnib(Zarnestra) 5mg $120 2021-12-16 Buy
ApexBio Technology A4227 Tipifarnib(Zarnestra) 10mM(in 1mL DMSO) $200 2021-12-16 Buy
ApexBio Technology A4227 Tipifarnib(Zarnestra) 25mg $400 2021-12-16 Buy
ApexBio Technology A4227 Tipifarnib(Zarnestra) 100mg $960 2021-12-16 Buy
Apolloscientific BIFK0043 Tipifarnib >98% 2mg $73 2021-12-16 Buy
Next Last

Properties

Melting point :211-213°C (dec.)
Boiling point :681.7±55.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :7.20±0.10(Predicted)
form :powder
color :white to beige
optical activity :[α]/D 17 to 24°, c = 1 in methanol
InChI :InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1
InChIKey :PLHJCIYEEKOWNM-HHHXNRCGSA-N
SMILES :N1(C)C2=C(C=C([C@](N)(C3=CC=C(Cl)C=C3)C3N(C)C=NC=3)C=C2)C(C2=CC=CC(Cl)=C2)=CC1=O

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

A farnesyltransferase inhibitor. Sensitizes human multiple myeloma cell to proteasome inhibition by blocking degradation of bortezomib(B675700)-induced aggresomes. Also shown to inhibit the growth of myeloid leukemia cell lines and primary leukemia cells by inducing apoptosis and cell-cycle blockage when combined with rapamycin(R124000).

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Suppliers and manufacturers

career henan chemical co
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$2.00 /1kg
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TargetMol Chemicals Inc.
Tipifarnib
$34.00 /1mg
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Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
CONIER CHEM AND PHARMA LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Chemia Biotechnology（Shanghai） Co., Ltd
Hefei Hirisun Pharmatech Co., Ltd
Zhejiang J&C Biological Technology Co.,Limited