Tiplaxtinin
|
- $49 - $1500
- Product name: Tiplaxtinin
- CAS: 393105-53-8
- MF: C24H16F3NO4
- MW: 439.38
- EINECS:
- MDL Number:MFCD09475615
- Synonyms:2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indol-3-yl)-2-oxoacetic acid;TIPLAXTININ(PAI-039);1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-;2-[1-benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxo-acetic aci d;Tiplaxtinin;PAI-039;alpha-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic acid;PAI 039 Tiplaxtinin
56 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 200mg
- 10mM*1mLinDMSO(Solution)
- 2x25mg
- 10mM(in 1mL DMSO)
- 50
- 10
- 250mg
- 10mM*1mLinDMSO
- 1mg
- 2mg
- 5mg
- 10mg
- 1G
- 25mg
- 50mg
- 100mg
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA0038O4
- Product description1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]- ≥98%
- Packaging1mg
- Price$49
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038O4
- Product description1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-
- Packaging2mg
- Price$50
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038O4
- Product description1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-
- Packaging5mg
- Price$68
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038O4
- Product description1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-
- Packaging10mg
- Price$90
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038O4
- Product description1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-
- Packaging25mg
- Price$145
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038O4
- Product description1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-
- Packaging50mg
- Price$239
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038O4
- Product description1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-
- Packaging100mg
- Price$451
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33835
- Product descriptionTiplaxtinin 98%
- Packaging1G
- Price$960
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33835
- Product descriptionTiplaxtinin 98%
- Packaging100MG
- Price$160
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number8764CP
- Product descriptionTiplasinin
- Packaging5mg
- Price$206
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8764CP
- Product descriptionTiplasinin
- Packaging50mg
- Price$687
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA363712
- Product descriptionTiplaxtinin 98+%
- Packaging25mg
- Price$211
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA363712
- Product descriptionTiplaxtinin 98+%
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA363712
- Product descriptionTiplaxtinin 98+%
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA363712
- Product descriptionTiplaxtinin 98+%
- Packaging50mg
- Price$274
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004725
- Product descriptionPAI-039 95.00%
- Packaging5MG
- Price$295.9
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0038O4 | 1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]- ≥98% | 1mg | $49 | 2026-05-28 | Buy |
| aablocks | AA0038O4 | 1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]- | 2mg | $50 | 2026-05-28 | Buy |
| aablocks | AA0038O4 | 1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]- | 5mg | $68 | 2026-05-28 | Buy |
| aablocks | AA0038O4 | 1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]- | 10mg | $90 | 2026-05-28 | Buy |
| aablocks | AA0038O4 | 1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]- | 25mg | $145 | 2026-05-28 | Buy |
| aablocks | AA0038O4 | 1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]- | 50mg | $239 | 2026-05-28 | Buy |
| aablocks | AA0038O4 | 1H-Indole-3-aceticacid, a-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]- | 100mg | $451 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33835 | Tiplaxtinin 98% | 1G | $960 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33835 | Tiplaxtinin 98% | 100MG | $160 | 2026-05-27 | Buy |
| AK Scientific | 8764CP | Tiplasinin | 5mg | $206 | 2021-12-16 | Buy |
| AK Scientific | 8764CP | Tiplasinin | 50mg | $687 | 2021-12-16 | Buy |
| Ambeed | A363712 | Tiplaxtinin 98+% | 25mg | $211 | 2021-12-16 | Buy |
| Ambeed | A363712 | Tiplaxtinin 98+% | 5mg | $84 | 2021-12-16 | Buy |
| Ambeed | A363712 | Tiplaxtinin 98+% | 10mg | $125 | 2021-12-16 | Buy |
| Ambeed | A363712 | Tiplaxtinin 98+% | 50mg | $274 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004725 | PAI-039 95.00% | 5MG | $295.9 | 2021-12-16 | Buy |
Properties
Melting point :164-167℃
Density :1.34
storage temp. :-20°C
solubility :DMSO (Sparingly), Methanol (Slightly)
form :powder
color :white to beige
InChI :InChI=1S/C24H16F3NO4/c25-24(26,27)32-18-9-6-16(7-10-18)17-8-11-21-19(12-17)20(22(29)23(30)31)14-28(21)13-15-4-2-1-3-5-15/h1-12,14H,13H2,(H,30,31)
InChIKey :ODXQFEWQSHNQNI-UHFFFAOYSA-N
SMILES :C1(C(=O)C(O)=O)=CN(C2C=CC(C3=CC=C(C=C3)OC(F)(F)F)=CC1=2)CC1C=CC=CC=1
Density :1.34
storage temp. :-20°C
solubility :DMSO (Sparingly), Methanol (Slightly)
form :powder
color :white to beige
InChI :InChI=1S/C24H16F3NO4/c25-24(26,27)32-18-9-6-16(7-10-18)17-8-11-21-19(12-17)20(22(29)23(30)31)14-28(21)13-15-4-2-1-3-5-15/h1-12,14H,13H2,(H,30,31)
InChIKey :ODXQFEWQSHNQNI-UHFFFAOYSA-N
SMILES :C1(C(=O)C(O)=O)=CN(C2C=CC(C3=CC=C(C=C3)OC(F)(F)F)=CC1=2)CC1C=CC=CC=1
Safety Information
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| Signal word: | Danger | ||||||||||||||||||||||||||||
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Description
Tiplaxtinin is an inhibitor of plasminogen activator inhibitor 1 (PAI-1; IC50 = 2.7 μM for the human enzyme). It inhibits differentiation of human adipocytes when used at a concentration of 5 μM. Tiplaxtinin (5 and 20 mg/kg) reduces tumor growth and microvessel density in a T24 bladder cancer mouse xenograft model. It prevents carotid artery occlusion, increases the time to occlusive thrombosis, and decreases the thrombus size in a rat model of ferric chloride-induced arterial thrombosis when administered at a dose of 1 mg/kg.Related product price
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