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ChemicalBook >> CAS DataBase List >> Toceranib

Toceranib

Toceranib price.
  • $36 - $9250
  • Product name: Toceranib
  • CAS: 356068-94-5
  • MF: C22H25FN4O2
  • MW: 396.46
  • EINECS:
  • MDL Number:MFCD16038046
  • Synonyms:(Z)-5-(5-Fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidenemethyl)-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrrole-3-carboxamide;SU-11654;Toceranib;(Z)-5-[(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide;5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylideneMethyl)-2,4-diMethyl-1H-pyrrole-3-carboxylic Acid (2-(Pyrrolidin-1-yl)ethyl)aMide;5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)Methyl]-2,4-diMethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrrole-3-carboxaMide;PHA 291639;5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylideneMethyl)-2,4-diMethyl-1H-pyrrole-3-carboxylic Acid (2-(Pyrrolidin-1-yl-d8)ethyl)aMide
29 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
Package
  • 1mg
  • 2mg
  • 5MG
  • 10mg
  • 25MG
  • 50MG
  • 100mg
  • 250mg
  • 1000mg
  • 1g
  • 50
  • 10
  • 5g
  • ManufacturerAK Scientific
  • Product number4124AH
  • Product descriptionToceranib
  • Packaging5g
  • Price$1131
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0163782
  • Product descriptionSU-11654 95.00%
  • Packaging5MG
  • Price$816.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0163782
  • Product descriptionSU-11654 95.00%
  • Packaging50MG
  • Price$2194.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3879
  • Product descriptionToceranib
  • Packaging10mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3879
  • Product descriptionToceranib
  • Packaging50mg
  • Price$457
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181175
  • Product descriptionToceranib(SU 11654; PHA 291639) >98%
  • Packaging100mg
  • Price$578
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181175
  • Product descriptionToceranib(SU 11654; PHA 291639) >98%
  • Packaging250mg
  • Price$1133.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181175
  • Product descriptionToceranib(SU 11654; PHA 291639) >98%
  • Packaging1000mg
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT44529
  • Product descriptionToceranib
  • Packaging1mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT44529
  • Product descriptionToceranib
  • Packaging2mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT44529
  • Product descriptionToceranib
  • Packaging5mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT44529
  • Product descriptionToceranib
  • Packaging10mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17714
  • Product descriptionToceranib ≥95%
  • Packaging1mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17714
  • Product descriptionToceranib ≥95%
  • Packaging5mg
  • Price$155
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17714
  • Product descriptionToceranib ≥95%
  • Packaging10mg
  • Price$274
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17714
  • Product descriptionToceranib ≥95%
  • Packaging50mg
  • Price$1105
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4124AH Toceranib 5g $1131 2021-12-16 Buy
American Custom Chemicals Corporation CHM0163782 SU-11654 95.00% 5MG $816.75 2021-12-16 Buy
American Custom Chemicals Corporation CHM0163782 SU-11654 95.00% 50MG $2194.5 2021-12-16 Buy
ApexBio Technology A3879 Toceranib 10mg $173 2021-12-16 Buy
ApexBio Technology A3879 Toceranib 50mg $457 2021-12-16 Buy
Biorbyt Ltd orb181175 Toceranib(SU 11654; PHA 291639) >98% 100mg $578 2021-12-16 Buy
Biorbyt Ltd orb181175 Toceranib(SU 11654; PHA 291639) >98% 250mg $1133.9 2021-12-16 Buy
Biorbyt Ltd orb181175 Toceranib(SU 11654; PHA 291639) >98% 1000mg $2245.7 2021-12-16 Buy
Biosynth Carbosynth FT44529 Toceranib 1mg $100 2021-12-16 Buy
Biosynth Carbosynth FT44529 Toceranib 2mg $150 2021-12-16 Buy
Biosynth Carbosynth FT44529 Toceranib 5mg $250 2021-12-16 Buy
Biosynth Carbosynth FT44529 Toceranib 10mg $450 2021-12-16 Buy
Cayman Chemical 17714 Toceranib ≥95% 1mg $36 2024-03-01 Buy
Cayman Chemical 17714 Toceranib ≥95% 5mg $155 2024-03-01 Buy
Cayman Chemical 17714 Toceranib ≥95% 10mg $274 2024-03-01 Buy
Cayman Chemical 17714 Toceranib ≥95% 50mg $1105 2024-03-01 Buy

Properties

Melting point :>133°C (dec.)
Boiling point :596.8±50.0 °C(Predicted)
Density :1.293
storage temp. :room temp
solubility :DMSO (Slightly, Heated), Methanol (Very Slightly, Heated)
form :powder
pka :11.70±0.20(Predicted)
color :yellow to orange

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Toceranib is a small molecule, multi-targeted receptor tyrosine kinase inhibitor that is structurally related to sunitinib . It potently inhibits signaling through VEGFR, FGFR, PDGFR, and Kit. Moveover, toceranib blocks the autophosphorylation of both wild type and mutant forms of Kit in response to stem cell factor, resulting in cell death. It is active in vivo and is commonly used against solid tumors in dogs.

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