U0126
|
- $49 - $1950
- Product name: U0126
- CAS: 109511-58-2
- MF: C18H16N6S2
- MW: 380.49
- EINECS:
- MDL Number:MFCD09971039
- Synonyms:U0126;1,4-DIAMINO-2,3-DICYANO-1,4-BIS(2-AMINOPHENYLTHIO)BUTADIENE;1,4-DIAMINO-2,3-DICYANO-1,4-BIS(2-AMINOPHYNYLTIO)BUTADIENE;1,4-DIAMINO-2,3-DICYANO-1,4-BIS(O-AMINOPHENYLMERCAPTO)BUTADIENE;1,4-DIAMINO-2,3-DICYANO-1;UO 126;U0126 >99%;2,3-Bis[amino[(2-aminophenyl)thio]methylene]butanedinitrile
71 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 200mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 5
- 1000mg
- 25
- 250mg
- 300mg
- 1mL(10mMinDMSO)
- 1mg
- 5mg
- 10mg
- 20mg
- 25MG
- 50mg
- 100MG
- 1G
- Manufactureraablocks
- Product numberAA008R7W
- Product descriptionU0126 ≥98%
- Packaging1mg
- Price$49
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008R7W
- Product descriptionU0126 ≥98%
- Packaging5mg
- Price$130
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008R7W
- Product descriptionU0126 99%
- Packaging10mg
- Price$164
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008R7W
- Product descriptionU0126 99%
- Packaging50mg
- Price$467
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU109061
- Product descriptionU0126 98.00%
- Packaging25MG
- Price$395
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU109061
- Product descriptionU0126 98.00%
- Packaging100MG
- Price$850
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU109061
- Product descriptionU0126 98.00%
- Packaging5MG
- Price$195
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU109061
- Product descriptionU0126 98.00%
- Packaging1G
- Price$1950
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberV2422
- Product description1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene
- Packaging5mg
- Price$229
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberBA2003
- Product descriptionU0126
- Packaging50mg
- Price$189
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA2003
- Product descriptionU0126
- Packaging20mg
- Price$108
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA2003
- Product descriptionU0126
- Packaging10mg
- Price$67
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA2003
- Product descriptionU0126
- Packaging1mL(10mMinDMSO)
- Price$76
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA2003
- Product descriptionU0126
- Packaging200mg
- Price$453
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA2003
- Product descriptionU0126
- Packaging100mg
- Price$311
- Updated2026-05-06
- Buy
- ManufacturerApolloscientific
- Product numberBIU1095
- Product descriptionU0126 98%
- Packaging25mg
- Price$517
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008R7W | U0126 ≥98% | 1mg | $49 | 2026-05-28 | Buy |
| aablocks | AA008R7W | U0126 ≥98% | 5mg | $130 | 2026-05-28 | Buy |
| aablocks | AA008R7W | U0126 99% | 10mg | $164 | 2026-05-28 | Buy |
| aablocks | AA008R7W | U0126 99% | 50mg | $467 | 2026-05-28 | Buy |
| ACHEMBLOCK | U109061 | U0126 98.00% | 25MG | $395 | 2026-05-27 | Buy |
| ACHEMBLOCK | U109061 | U0126 98.00% | 100MG | $850 | 2026-05-27 | Buy |
| ACHEMBLOCK | U109061 | U0126 98.00% | 5MG | $195 | 2026-05-27 | Buy |
| ACHEMBLOCK | U109061 | U0126 98.00% | 1G | $1950 | 2026-05-27 | Buy |
| AK Scientific | V2422 | 1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene | 5mg | $229 | 2021-12-16 | Buy |
| ApexBio Technology | BA2003 | U0126 | 50mg | $189 | 2026-05-06 | Buy |
| ApexBio Technology | BA2003 | U0126 | 20mg | $108 | 2026-05-06 | Buy |
| ApexBio Technology | BA2003 | U0126 | 10mg | $67 | 2026-05-06 | Buy |
| ApexBio Technology | BA2003 | U0126 | 1mL(10mMinDMSO) | $76 | 2026-05-06 | Buy |
| ApexBio Technology | BA2003 | U0126 | 200mg | $453 | 2026-05-06 | Buy |
| ApexBio Technology | BA2003 | U0126 | 100mg | $311 | 2026-05-06 | Buy |
| Apolloscientific | BIU1095 | U0126 98% | 25mg | $517 | 2026-06-04 | Buy |
Properties
Melting point :approximate 154℃(dec.)
Boiling point :565.1±50.0 °C(Predicted)
Density :1.44
RTECS :EJ9710000
storage temp. :Desiccate at +4°C
solubility :Soluble in DMSO (up to 200 mg/ml).
form :White solid
pka :2.11±0.10(Predicted)
color :White
Water Solubility :Soluble in DMSO. Poorly soluble in ethanol and water
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :1S/C18H16N6S2/c19-9-11(17(23)25-15-7-3-1-5-13(15)21)12(10-20)18(24)26-16-8-4-2-6-14(16)22/h1-8H,21-24H2/b17-11+,18-12+
InChIKey :DVEXZJFMOKTQEZ-JYFOCSDGSA-N
SMILES :S(c2c(cccc2)N)\C(=C(\C(=C(\Sc1c(cccc1)N)/N)\C#N)/C#N)\N
Boiling point :565.1±50.0 °C(Predicted)
Density :1.44
RTECS :EJ9710000
storage temp. :Desiccate at +4°C
solubility :Soluble in DMSO (up to 200 mg/ml).
form :White solid
pka :2.11±0.10(Predicted)
color :White
Water Solubility :Soluble in DMSO. Poorly soluble in ethanol and water
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :1S/C18H16N6S2/c19-9-11(17(23)25-15-7-3-1-5-13(15)21)12(10-20)18(24)26-16-8-4-2-6-14(16)22/h1-8H,21-24H2/b17-11+,18-12+
InChIKey :DVEXZJFMOKTQEZ-JYFOCSDGSA-N
SMILES :S(c2c(cccc2)N)\C(=C(\C(=C(\Sc1c(cccc1)N)/N)\C#N)/C#N)\N
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
U-0126 is a selective MAP Kinase Kinase (MKK, MEK) inhibitor with IC50 values of 72 nM and 58 nM for MEK1 and MEK2, respectively. It shows little to no inhibition against a number of other kinases including PKC, Ab1, Raf, MEKK, ERK, JNK, MKK-3, MKK-4, MKK-6, Cdk2, and Cdk4. U-0126 inhibition of MEK is noncompetitive with respect adenosine triphosphate (ATP) and its phosphorylation target ERK, which may partially explain its selectivity profile against other kinases.Related product price
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Suppliers and manufacturers
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
Chembest Research Laboratories Limited
Ascent Scientific
Chemsky (shanghai) International Co.,Ltd
Jinan Trio PharmaTech Co., Ltd.
Tianjin YongSheng Biotechnology Co., Ltd.
NCE Biomedical Co.,Ltd.
Nanjing Norris-Pharm Technology Co., Ltd
China Kouting Group Limited