VR23
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- $15 - $1192
- Product name: VR23
- CAS: 1624602-30-7
- MF: C19H16ClN5O6S
- MW: 477.88
- EINECS:
- MDL Number:MFCD28502093
- Synonyms:VR23;7-Chloro-4-[4-[(2,4-dinitrophenyl)sulfonyl]-1-piperazinyl]quinoline;VR23(VR-23);7-chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline;CS-1579;Quinoline, 7-chloro-4-[4-[(2,4-dinitrophenyl)sulfonyl]-1-piperazinyl]-;VR23 >=98% (HPLC);VR23, 10 mM in DMSO
35 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Ark Pharm
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5 mg
- 25 mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3676-M005
- Product descriptionVR23[ProteasomeInhibitor] ≥98%(HPLC)
- Packaging5mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6718DW
- Product descriptionCID73442847
- Packaging10mg
- Price$402
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6718DW
- Product descriptionCID73442847
- Packaging25mg
- Price$714
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA142790
- Product description7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+%
- Packaging1mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA142790
- Product description7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+%
- Packaging5mg
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA142790
- Product description7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+%
- Packaging10mg
- Price$46
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA142790
- Product description7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+%
- Packaging25mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA142790
- Product description7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+%
- Packaging50mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA142790
- Product description7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+%
- Packaging100mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA142790
- Product description7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+%
- Packaging250mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA142790
- Product description7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+%
- Packaging1g
- Price$455
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004688
- Product descriptionVR23 95.00%
- Packaging5MG
- Price$501.13
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6026
- Product descriptionVR23
- Packaging5mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6026
- Product descriptionVR23
- Packaging25mg
- Price$335
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000042533
- Product descriptionVR23 98+%
- Packaging1mg
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000042533
- Product descriptionVR23 98+%
- Packaging5mg
- Price$95
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3676-M005 | VR23[ProteasomeInhibitor] ≥98%(HPLC) | 5mg | $85 | 2021-12-16 | Buy |
| AK Scientific | 6718DW | CID73442847 | 10mg | $402 | 2021-12-16 | Buy |
| AK Scientific | 6718DW | CID73442847 | 25mg | $714 | 2021-12-16 | Buy |
| Ambeed | A142790 | 7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+% | 1mg | $15 | 2021-12-16 | Buy |
| Ambeed | A142790 | 7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+% | 5mg | $32 | 2021-12-16 | Buy |
| Ambeed | A142790 | 7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+% | 10mg | $46 | 2021-12-16 | Buy |
| Ambeed | A142790 | 7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+% | 25mg | $70 | 2021-12-16 | Buy |
| Ambeed | A142790 | 7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+% | 50mg | $95 | 2021-12-16 | Buy |
| Ambeed | A142790 | 7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+% | 100mg | $133 | 2021-12-16 | Buy |
| Ambeed | A142790 | 7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+% | 250mg | $200 | 2021-12-16 | Buy |
| Ambeed | A142790 | 7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+% | 1g | $455 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004688 | VR23 95.00% | 5MG | $501.13 | 2021-12-16 | Buy |
| ApexBio Technology | B6026 | VR23 | 5mg | $95 | 2021-12-16 | Buy |
| ApexBio Technology | B6026 | VR23 | 25mg | $335 | 2021-12-16 | Buy |
| Ark Pharm | P000042533 | VR23 98+% | 1mg | $56 | 2021-12-16 | Buy |
| Ark Pharm | P000042533 | VR23 98+% | 5mg | $95 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥45.55 mg/mL in DMSO
form :Powder
color :Light yellow to yellow
solubility :insoluble in EtOH; insoluble in H2O; ≥45.55 mg/mL in DMSO
form :Powder
color :Light yellow to yellow
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
VR23 is a chloroquine derivative that functions as a proteasome inhibitor (IC50s = 1 nM, 50-100 nM, and 3 μM for trypsin-like, chymotrypsin-like, and caspase-like proteasomes, respectively). It also deregulates the activity of cyclin E and other centrosomal proteins, resulting in the induction of multiple centrosome amplification, abnormal spindle formation, uneven cytokinesis, irreversible mitotic arrest, and eventually apoptosis that is specific to cancer cells. In combination with the chymotrypsin-like proteasome inhibitor bortezomib , VR23 can produce a synergistic effect in killing multiple myeloma cells, including those that are resistant to bortezomib.More related product prices
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