VcMMAE
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- $28 - $6247.5
- Product name: VcMMAE
- CAS: 646502-53-6
- MF: C68H105N11O15
- MW: 1316.63
- EINECS:
- MDL Number:MFCD25372036
- Synonyms:VcMMAE;Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E;4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl((S)-1-(((S)-1-(((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-y;MC-VC-PAB-MMAE,MC-Val-Cit-PAB-MMAE;maleimido-caproyl-val-Cit-PAB-MMAE;VeMMAE;EOS-60990;4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-Uriedidopenamiamido)benzyl((S)-1-(((S)-1-(((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S),2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-y
67 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Ambeed
- Arctom
- Biorbyt Ltd
- Biosynth
- BroadPharm
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
Package
- 1mg
- 5mg
- 10.00mg
- 10mg
- 25mg
- 25.00mg
- 0.025g
- 50.00mg
- 0.05g
- 50mg
- 0.1g
- 100mg
- 250mg
- 0.25g
- 500mg
- 0.5g
- 1g
- 5g
- Manufactureraablocks
- Product numberAA0035PP
- Product descriptionMaleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E ≥98%
- Packaging1mg
- Price$28
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035PP
- Product descriptionMaleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98%
- Packaging5mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035PP
- Product descriptionMaleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98%
- Packaging10mg
- Price$64
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035PP
- Product descriptionMaleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E
- Packaging25mg
- Price$151
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035PP
- Product descriptionMaleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98%
- Packaging50mg
- Price$187
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035PP
- Product descriptionMaleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98%
- Packaging100mg
- Price$255
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035PP
- Product descriptionMaleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98%
- Packaging250mg
- Price$370
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035PP
- Product descriptionMaleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98%
- Packaging1g
- Price$1192
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ70231
- Product descriptionMc-Val-Cit-PAB-MMAE 97%
- Packaging100MG
- Price$440
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ70231
- Product descriptionMc-Val-Cit-PAB-MMAE 97%
- Packaging1G
- Price$2450
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ70231
- Product descriptionMc-Val-Cit-PAB-MMAE 97%
- Packaging25MG
- Price$150
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ70231
- Product descriptionMc-Val-Cit-PAB-MMAE 97%
- Packaging5MG
- Price$45
- Updated2026-05-27
- Buy
- ManufacturerAmbeed
- Product numberA153774
- Product descriptionVcMMAE 98+%
- Packaging1mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA153774
- Product descriptionVcMMAE 98+%
- Packaging25mg
- Price$1760
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA153774
- Product descriptionVcMMAE 98+%
- Packaging5mg
- Price$570
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA153774
- Product descriptionVcMMAE 98+%
- Packaging10mg
- Price$955
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0035PP | Maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E ≥98% | 1mg | $28 | 2026-05-28 | Buy |
| aablocks | AA0035PP | Maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98% | 5mg | $36 | 2026-05-28 | Buy |
| aablocks | AA0035PP | Maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98% | 10mg | $64 | 2026-05-28 | Buy |
| aablocks | AA0035PP | Maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E | 25mg | $151 | 2026-05-28 | Buy |
| aablocks | AA0035PP | Maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98% | 50mg | $187 | 2026-05-28 | Buy |
| aablocks | AA0035PP | Maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98% | 100mg | $255 | 2026-05-28 | Buy |
| aablocks | AA0035PP | Maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98% | 250mg | $370 | 2026-05-28 | Buy |
| aablocks | AA0035PP | Maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E 98% | 1g | $1192 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q70231 | Mc-Val-Cit-PAB-MMAE 97% | 100MG | $440 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q70231 | Mc-Val-Cit-PAB-MMAE 97% | 1G | $2450 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q70231 | Mc-Val-Cit-PAB-MMAE 97% | 25MG | $150 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q70231 | Mc-Val-Cit-PAB-MMAE 97% | 5MG | $45 | 2026-05-27 | Buy |
| Ambeed | A153774 | VcMMAE 98+% | 1mg | $210 | 2021-12-16 | Buy |
| Ambeed | A153774 | VcMMAE 98+% | 25mg | $1760 | 2021-12-16 | Buy |
| Ambeed | A153774 | VcMMAE 98+% | 5mg | $570 | 2021-12-16 | Buy |
| Ambeed | A153774 | VcMMAE 98+% | 10mg | $955 | 2021-12-16 | Buy |
Properties
Boiling point :1347.6±65.0 °C(Predicted)
Density :1.196±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO, DCM, DMF
form :A solid
pka :13.29±0.70(Predicted)
color :White to off-white
InChIKey :NLMBVBUNULOTNS-NNNQBTKHNA-N
Density :1.196±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO, DCM, DMF
form :A solid
pka :13.29±0.70(Predicted)
color :White to off-white
InChIKey :NLMBVBUNULOTNS-NNNQBTKHNA-N
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
VcMMAE is a MMAE derivative with valine-citrulline (Vc) linker. VcMMAE can be used to make antibody drug conjugate. VcMMAE is a anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc). Monomethyl auristatin E (MMAE) is a synthetic antineoplastic agent. Because of its toxicity, it cannot be used as a drug itself; instead, it is linked to a monoclonal antibody (MAB) which directs it to the cancer cells. In International Nonproprietary Names for MMAE-MAB-conjugates, the name vedotin refers to MMAE plus its linking structure to the antibody. It is a potent antimitotic drug derived from peptides occurring in marine shell-less mollusc Dolabella auricularia called dolastatins which show potent activity in preclinical studies, both in vitro and in vivo, against a range of lymphomas, leukemia and solid tumors. These drugs show potency of up to 200 times that of vinblastine, another antimitotic drug used for Hodgkin lymphoma as well as other types of cancer?Related product price
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