Vorapaxar
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- $25 - $3791
- Product name: Vorapaxar
- CAS: 618385-01-6
- MF: C29H33FN2O4
- MW: 492.58
- EINECS:
- MDL Number:MFCD16038876
- Synonyms:Vorapaxar;Voarapaxar;Ethyl [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]vinyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamate;[(1R,3AR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-me;Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester;CS-1663;CS-2015;ethyl((1R,3aR,4aR,8aR,9aS)-9-((E)-2-(5-(3-fluorophenyl)pyridin-2-yl)vinyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate
68 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
Package
- 10mM(in 1mL DMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- 1unit
- EvaluationSample
- 250mg
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solution)
- 10mM(1mLinDMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1G
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA00ECDR
- Product descriptionCarbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98%
- Packaging1mg
- Price$25
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ECDR
- Product descriptionCarbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98%(HPLC)
- Packaging5mg
- Price$42
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ECDR
- Product descriptionCarbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98%(HPLC)
- Packaging10mg
- Price$62
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ECDR
- Product descriptionCarbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98%(HPLC)
- Packaging25mg
- Price$104
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ECDR
- Product descriptionCarbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98%(HPLC)
- Packaging50mg
- Price$162
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ECDR
- Product descriptionCarbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98%(HPLC)
- Packaging100mg
- Price$248
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16064
- Product descriptionVorapaxar 98%
- Packaging100MG
- Price$210
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16064
- Product descriptionVorapaxar 98%
- Packaging25MG
- Price$90
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16064
- Product descriptionVorapaxar 98%
- Packaging5MG
- Price$35
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16064
- Product descriptionVorapaxar 98%
- Packaging1G
- Price$1450
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberJ96880
- Product descriptionVorapaxar
- Packaging25mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY1927
- Product descriptionVorapaxar
- Packaging1mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ96880
- Product descriptionVorapaxar
- Packaging10mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007774
- Product descriptionVORAPAXAR 95.00%
- Packaging5MG
- Price$341
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8809
- Product descriptionVorapaxar
- Packaging10mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8809
- Product descriptionVorapaxar
- Packaging10mg
- Price$253
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ECDR | Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98% | 1mg | $25 | 2026-05-28 | Buy |
| aablocks | AA00ECDR | Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98%(HPLC) | 5mg | $42 | 2026-05-28 | Buy |
| aablocks | AA00ECDR | Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98%(HPLC) | 10mg | $62 | 2026-05-28 | Buy |
| aablocks | AA00ECDR | Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98%(HPLC) | 25mg | $104 | 2026-05-28 | Buy |
| aablocks | AA00ECDR | Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98%(HPLC) | 50mg | $162 | 2026-05-28 | Buy |
| aablocks | AA00ECDR | Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester 98%(HPLC) | 100mg | $248 | 2026-05-28 | Buy |
| ACHEMBLOCK | R16064 | Vorapaxar 98% | 100MG | $210 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16064 | Vorapaxar 98% | 25MG | $90 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16064 | Vorapaxar 98% | 5MG | $35 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16064 | Vorapaxar 98% | 1G | $1450 | 2026-05-27 | Buy |
| AK Scientific | J96880 | Vorapaxar | 25mg | $600 | 2021-12-16 | Buy |
| AK Scientific | Y1927 | Vorapaxar | 1mg | $51 | 2021-12-16 | Buy |
| AK Scientific | J96880 | Vorapaxar | 10mg | $288 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007774 | VORAPAXAR 95.00% | 5MG | $341 | 2021-12-16 | Buy |
| ApexBio Technology | A8809 | Vorapaxar | 10mg | $252 | 2021-12-16 | Buy |
| ApexBio Technology | A8809 | Vorapaxar | 10mg | $253 | 2026-05-06 | Buy |
Properties
Boiling point :676.0±55.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Store at -20° C
solubility :≥24.65 mg/mL in DMSO; insoluble in H2O; ≥10.64 mg/mL in EtOH with ultrasonic
form :solid
pka :12.49±0.60(Predicted)
color :White to off-white
InChIKey :ZBGXUVOIWDMMJE-QHNZEKIYSA-N
SMILES :C(OCC)(=O)N[C@@H]1CC[C@]2([H])[C@@]([H])(C1)C[C@@]1([H])C(=O)O[C@H](C)[C@@]1([H])[C@H]2/C=C/C1=NC=C(C2=CC=CC(F)=C2)C=C1
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Store at -20° C
solubility :≥24.65 mg/mL in DMSO; insoluble in H2O; ≥10.64 mg/mL in EtOH with ultrasonic
form :solid
pka :12.49±0.60(Predicted)
color :White to off-white
InChIKey :ZBGXUVOIWDMMJE-QHNZEKIYSA-N
SMILES :C(OCC)(=O)N[C@@H]1CC[C@]2([H])[C@@]([H])(C1)C[C@@]1([H])C(=O)O[C@H](C)[C@@]1([H])[C@H]2/C=C/C1=NC=C(C2=CC=CC(F)=C2)C=C1
Safety Information
| Symbol(GHS): |
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Description
Vorapaxar is an orally bioavailable competitive antagonist of the proteinase-activated receptor (PAR1; Ki = 8.1 nM), also known as the thrombin receptor. It is selective for PAR1 over other PARs, as well as a number of GPCRs, ion channels, and receptors. It inhibits platelet aggregation induced by thrombin and haTRAP (IC50s = 47 and 25 nM, respectively). Vorapaxar (0.1 mg/kg, i.v.) completely inhibits platelet aggregation in cynomolgus monkeys ex vivo. Formulations containing vorapaxar are used in the prevention of thrombotic cardiovascular events.Related product price
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