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ChemicalBook >> CAS DataBase List >> XL888

XL888

$49 - $4321.4
Product name: XL888
CAS: 1149705-71-4
MF: C29H37N5O3
MW: 503.64
EINECS:
MDL Number:
Synonyms:1,4-Benzenedicarboxamide, N1-[(3-endo)-8-[5-(cyclopropylcarbonyl)-2-pyridinyl]-8-azabicyclo[3.2.1]oct-3-yl]-2-methyl-5-[[(1R)-1-methylpropyl]amino]-;XL 888, >=98%;XL888;5-((R)-sec-butylaMino)-N1-((1R,3r,5S)-8-(5-(cyclopropanecarbonyl)pyridin-2-yl)-8-azabicyclo[3.2.1]octan-3-yl)-2-MethylterephthalaMide;N1-[(3-endo)-8-[5-(Cyclopropylcarbonyl)-2-pyridinyl]-8-azabicyclo[3.2.1]oct-3-yl]-2-methyl-5-[[(1R)-1-methylpropyl]amino]-1,4-benzenedicarboxamide;CS-831;CS-2629;XL888; XL-888; XL 888

Price31 Properties Safety Information Description

31 prices

Selected condition：

Brand

AK Scientific
ApexBio Technology
Biorbyt Ltd
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
TRC

Package

1mg
5mg
10mg
25mg
50mg
100mg
250mg
1g
10mM(in1mLDMSO)

ManufacturerAK Scientific
Product number2810AH
Product description2-[[(2R)-Butan-2-yl]amino]-4-N-[(1S,5R)-8-[5-(cyclopropanecarbonyl)pyridin-2-yl]-8-azabicyclo[3.2.1]octan-3-yl]-5-methylbenzene-1,4-dicarboxamide
Packaging1mg
Price$101
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2810AH
Product description2-[[(2R)-Butan-2-yl]amino]-4-N-[(1S,5R)-8-[5-(cyclopropanecarbonyl)pyridin-2-yl]-8-azabicyclo[3.2.1]octan-3-yl]-5-methylbenzene-1,4-dicarboxamide
Packaging5mg
Price$250
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2810AH
Product description2-[[(2R)-Butan-2-yl]amino]-4-N-[(1S,5R)-8-[5-(cyclopropanecarbonyl)pyridin-2-yl]-8-azabicyclo[3.2.1]octan-3-yl]-5-methylbenzene-1,4-dicarboxamide
Packaging10mg
Price$367
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4388
Product descriptionXL-888
Packaging10mg
Price$275
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA4388
Product descriptionXL-888
Packaging5mg
Price$160
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4388
Product descriptionXL-888
Packaging5mg
Price$176
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA4388
Product descriptionXL-888
Packaging10mM(in1mLDMSO)
Price$187
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA4388
Product descriptionXL-888
Packaging25mg
Price$484
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA4388
Product descriptionXL-888
Packaging50mg
Price$825
Updated2026-05-06
Buy

ManufacturerBiorbyt Ltd
Product numberorb180877
Product descriptionXL888 >98%
Packaging100mg
Price$1208.7
Updated2021-12-16
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ManufacturerBiorbyt Ltd
Product numberorb180877
Product descriptionXL888 >98%
Packaging250mg
Price$2245.7
Updated2021-12-16
Buy

ManufacturerBiorbyt Ltd
Product numberorb180877
Product descriptionXL888 >98%
Packaging1g
Price$4321.4
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number16309
Product descriptionXL888 ≥98%
Packaging25mg
Price$593
Updated2024-03-01
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ManufacturerCayman Chemical
Product number16309
Product descriptionXL888 ≥98%
Packaging25mg
Price$653
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number16309
Product descriptionXL888 ≥98%
Packaging5mg
Price$216
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number16309
Product descriptionXL888 ≥98%
Packaging5mg
Price$238
Updated2026-04-30
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	2810AH	2-[[(2R)-Butan-2-yl]amino]-4-N-[(1S,5R)-8-[5-(cyclopropanecarbonyl)pyridin-2-yl]-8-azabicyclo[3.2.1]octan-3-yl]-5-methylbenzene-1,4-dicarboxamide	1mg	$101	2021-12-16	Buy
AK Scientific	2810AH	2-[[(2R)-Butan-2-yl]amino]-4-N-[(1S,5R)-8-[5-(cyclopropanecarbonyl)pyridin-2-yl]-8-azabicyclo[3.2.1]octan-3-yl]-5-methylbenzene-1,4-dicarboxamide	5mg	$250	2021-12-16	Buy
AK Scientific	2810AH	2-[[(2R)-Butan-2-yl]amino]-4-N-[(1S,5R)-8-[5-(cyclopropanecarbonyl)pyridin-2-yl]-8-azabicyclo[3.2.1]octan-3-yl]-5-methylbenzene-1,4-dicarboxamide	10mg	$367	2021-12-16	Buy
ApexBio Technology	A4388	XL-888	10mg	$275	2026-05-06	Buy
ApexBio Technology	A4388	XL-888	5mg	$160	2021-12-16	Buy
ApexBio Technology	A4388	XL-888	5mg	$176	2026-05-06	Buy
ApexBio Technology	A4388	XL-888	10mM(in1mLDMSO)	$187	2026-05-06	Buy
ApexBio Technology	A4388	XL-888	25mg	$484	2026-05-06	Buy
ApexBio Technology	A4388	XL-888	50mg	$825	2026-05-06	Buy
Biorbyt Ltd	orb180877	XL888 >98%	100mg	$1208.7	2021-12-16	Buy
Biorbyt Ltd	orb180877	XL888 >98%	250mg	$2245.7	2021-12-16	Buy
Biorbyt Ltd	orb180877	XL888 >98%	1g	$4321.4	2021-12-16	Buy
Cayman Chemical	16309	XL888 ≥98%	25mg	$593	2024-03-01	Buy
Cayman Chemical	16309	XL888 ≥98%	25mg	$653	2026-04-30	Buy
Cayman Chemical	16309	XL888 ≥98%	5mg	$216	2024-03-01	Buy
Cayman Chemical	16309	XL888 ≥98%	5mg	$238	2026-04-30	Buy

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Properties

Boiling point :695.1±55.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥18.2 mg/mL in DMSO
form :solid
pka :14.33±0.20(Predicted)
color :Off-white to light yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Heat shock protein 90 (Hsp90) is a chaperone that maintains the functionality of client proteins involved in cell proliferation, cell cycling, and apoptosis. XL888 is an ATP-competitive inhibitor of Hsp90. Through this action, specific client proteins are degraded, resulting in cell cycle arrest or apoptosis. XL888 is orally bioavailable and shows efficacy in tumor regression in gastric carcinoma and melanoma xenografts in mice.

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Suppliers and manufacturers

TargetMol Chemicals Inc.

$43.00 /1mg
XL888 CAS:1149705-71-4

ATK CHEMICAL COMPANY LIMITED

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Dideu Industries Group Limited

Zhejiang J&C Biological Technology Co.,Limited

InvivoChem

TargetMol Chemicals Inc.

ShenZhen Trendseen Biological Technology Co.,Ltd.

Wuhan Topule Biopharmaceutical Co., Ltd

HANGZHOU LEAP CHEM CO., LTD.

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XL888

Properties

Safety Information

Description

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