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ChemicalBook >> CAS DataBase List >> YC-1

YC-1

YC-1 price.
  • $18 - $1500
  • Product name: YC-1
  • CAS: 170632-47-0
  • MF: C19H16N2O2
  • MW: 304.34
  • EINECS:
  • MDL Number:MFCD06407798
  • Synonyms:2-Furanmethanol, 5-[1-(phenylmethyl)-1H-indazol-3-yl]-;Nsc728165;(5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)Methanol;YC 1 (pharMaceutical);1-Benzyl-3-(5-hydroxymethylfur-2-yl)indazole;1-benzyl-3-(5-hydroxymethyl-furan-2-yl)indazole;Lificiguat(YC-1);5-[1-(PHENYLMETHYL)-1H-INDAZOL-3-YL]-2-FURANMETHANOL
43 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 50
  • 1mg
  • 5mg
  • 10
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0120-M001
  • Product descriptionYC-1 ≥98%(HPLC)
  • Packaging1mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4164AH
  • Product description5-[1-(Phenylmethyl)-1H-indazol-3-yl]-2-furanmethanol
  • Packaging5mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA174113
  • Product description(5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol 98+%
  • Packaging5mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA174113
  • Product description(5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol 98+%
  • Packaging10mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA174113
  • Product description(5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol 98+%
  • Packaging100mg
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA174113
  • Product description(5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol 98+%
  • Packaging250mg
  • Price$338
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA174113
  • Product description(5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol 98+%
  • Packaging1g
  • Price$881
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7641
  • Product descriptionYC-1
  • Packaging5mg
  • Price$87
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7641
  • Product descriptionYC-1
  • Packaging10mM(in 1mL DMSO)
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7641
  • Product descriptionYC-1
  • Packaging10mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7641
  • Product descriptionYC-1
  • Packaging50mg
  • Price$443
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7641
  • Product descriptionYC-1
  • Packaging100mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7641
  • Product descriptionYC-1
  • Packaging200mg
  • Price$1215
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS721069
  • Product description(5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol ≥98%
  • Packaging5mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS721069
  • Product description(5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol ≥98%
  • Packaging10mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS721069
  • Product description(5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol ≥98%
  • Packaging50mg
  • Price$130
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-0120-M001 YC-1 ≥98%(HPLC) 1mg $20 2021-12-16 Buy
AK Scientific 4164AH 5-[1-(Phenylmethyl)-1H-indazol-3-yl]-2-furanmethanol 5mg $116 2021-12-16 Buy
Ambeed A174113 (5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol 98+% 5mg $34 2021-12-16 Buy
Ambeed A174113 (5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol 98+% 10mg $48 2021-12-16 Buy
Ambeed A174113 (5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol 98+% 100mg $235 2021-12-16 Buy
Ambeed A174113 (5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol 98+% 250mg $338 2021-12-16 Buy
Ambeed A174113 (5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol 98+% 1g $881 2021-12-16 Buy
ApexBio Technology B7641 YC-1 5mg $87 2021-12-16 Buy
ApexBio Technology B7641 YC-1 10mM(in 1mL DMSO) $96 2021-12-16 Buy
ApexBio Technology B7641 YC-1 10mg $116 2021-12-16 Buy
ApexBio Technology B7641 YC-1 50mg $443 2021-12-16 Buy
ApexBio Technology B7641 YC-1 100mg $765 2021-12-16 Buy
ApexBio Technology B7641 YC-1 200mg $1215 2021-12-16 Buy
Arctom AS721069 (5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol ≥98% 5mg $34 2021-12-16 Buy
Arctom AS721069 (5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol ≥98% 10mg $48 2021-12-16 Buy
Arctom AS721069 (5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)methanol ≥98% 50mg $130 2021-12-16 Buy

Properties

Melting point :110-112℃
Boiling point :522.2±50.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: 12 mg/mL
pka :13.83±0.10(Predicted)
form :solid
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

YC-1 is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase. It inhibits collagen (10 μg/ml) and thrombin (0.1 U/ml) induced platelet aggregation with IC50 values of 11.7-14.6 and 57.3-59.3 μM, respectively. In the absence of NO or carbon monoxide (CO), 200 μM YC-1 increases the activity of purified soluble guanylyl cyclase 12-fold, with an ED50 value of 20 μM. At a concentration of 200 μM, YC-1 potentiates the maximal activity of soluble guanylyl cyclase in the presence of NO or CO by 40% and >3,000%, respectively.

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