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ChemicalBook >> CAS DataBase List >> ZEBULARINE

ZEBULARINE

ZEBULARINE price.
  • $8 - $1200
  • Product name: ZEBULARINE
  • CAS: 3690-10-6
  • MF: C9H12N2O5
  • MW: 228.2
  • EINECS:2017-001-1
  • MDL Number:MFCD04973699
  • Synonyms:4-Deoyuridine;1-b-D-ribofuranosyl-2-(1H)-pyriMidinone;anticancer drug, DNA Methylation inhibitor;2(1H)-Pyrimidinone, 1-β-D-ribofuranosyl-;2-Pyrimidone-1-β-D-riboside;1-beta-D-Ribofuranosyl-2(1H)-pyrimidinone;Pyrimidin-2-one beta-D-ribofuranoside;1-(β-d-ribofuranosyl)-1,2-dihydropyrimidin-2-one
39 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 10mM(in 1mL DMSO)
  • 50mg
  • 100mg
  • 200MG
  • 250mg
  • 500mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product number2817AH
  • Product descriptionZebularine
  • Packaging250mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1915
  • Product descriptionZebularine
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1915
  • Product descriptionZebularine
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1915
  • Product descriptionZebularine
  • Packaging50mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIA8416
  • Product descriptionZebularine
  • Packaging50mg
  • Price$203
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIA8416
  • Product descriptionZebularine
  • Packaging100mg
  • Price$319
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS459323
  • Product descriptionZebularine ≥98%
  • Packaging5mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS459323
  • Product descriptionZebularine ≥98%
  • Packaging10mg
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS459323
  • Product descriptionZebularine ≥98%
  • Packaging50mg
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS459323
  • Product descriptionZebularine ≥98%
  • Packaging250mg
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS459323
  • Product descriptionZebularine ≥98%
  • Packaging1g
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS459323
  • Product descriptionZebularine ≥98%
  • Packaging5g
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1254
  • Product descriptionZebularine 99%
  • Packaging10mg
  • Price$104.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND09503
  • Product description4-Deoxyuridine
  • Packaging100mg
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND09503
  • Product description4-Deoxyuridine
  • Packaging250mg
  • Price$132.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND09503
  • Product description4-Deoxyuridine
  • Packaging500mg
  • Price$210
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2817AH Zebularine 250mg $228 2021-12-16 Buy
ApexBio Technology A1915 Zebularine 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A1915 Zebularine 10mg $70 2021-12-16 Buy
ApexBio Technology A1915 Zebularine 50mg $280 2021-12-16 Buy
Apolloscientific BIA8416 Zebularine 50mg $203 2021-12-16 Buy
Apolloscientific BIA8416 Zebularine 100mg $319 2021-12-16 Buy
Arctom AS459323 Zebularine ≥98% 5mg $8 2021-12-16 Buy
Arctom AS459323 Zebularine ≥98% 10mg $10 2021-12-16 Buy
Arctom AS459323 Zebularine ≥98% 50mg $17 2021-12-16 Buy
Arctom AS459323 Zebularine ≥98% 250mg $33 2021-12-16 Buy
Arctom AS459323 Zebularine ≥98% 1g $72 2021-12-16 Buy
Arctom AS459323 Zebularine ≥98% 5g $238 2021-12-16 Buy
Axon Medchem Axon1254 Zebularine 99% 10mg $104.5 2021-12-16 Buy
Biosynth Carbosynth ND09503 4-Deoxyuridine 100mg $63 2021-12-16 Buy
Biosynth Carbosynth ND09503 4-Deoxyuridine 250mg $132.5 2021-12-16 Buy
Biosynth Carbosynth ND09503 4-Deoxyuridine 500mg $210 2021-12-16 Buy

Properties

Melting point :160-162?C
Boiling point :499.0±55.0 °C(Predicted)
Density :1.73±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 16 mg/mL, soluble
form :solid
pka :13.48±0.70(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
InChIKey :RPQZTTQVRYEKCR-WCTZXXKLSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.

Description

Zebularine, a cytidine analog, is a DNA methylation inhibitor that acts by forming a covalent complex with DNA methyltransferases (DNMTs). By stabilizing the binding of DNMTs to DNA, zebularine hinders methylation and decreases dissociation, trapping DNMT and preventing its turnover. Zebularine preferentially targets cancer cells in various human carcinoma cell lines demonstrating IC20 values of 20, 10, 20, and 5 μM for reducing proliferation of TK6, Jurkat, KG-1, and HCT116 cells, respectively. Zebularine exhibits low toxicity in mice even after prolonged administration (0.2 mg/mL drinking water for 113 days in a mouse intestinal cancer model).

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