ailanthone
|
- $41 - $1007
- Product name: ailanthone
- CAS: 981-15-7
- MF: C20H24O7
- MW: 376.4
- EINECS:
- MDL Number:MFCD01729487
- Synonyms:11β,20-Epoxy-1β,11,12α-trihydroxypicrasa-3,13(21)-diene-2,16-dione;13,21-Didehydrochaparrinone;ailanthone;Picrasa-3,13(21)-diene-2,16-dione,11,20-epoxy-1,11,12-trihydroxy-, (1b,11b,12a)-;Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-, (1β,11β,12α)-;(1beta,11alpha,12alpha)-1,11,12-trihydroxy-11,20-epoxypicras...;2H-1,11c-(Epoxymethano)phenanthro[10,1-bc]pyran-5,10(3H,6aH);(1β,11β,12α)-11,20-Epoxy-1,11,12-trihydroxypicrasa-3,13(21)-diene-2,16-dione
35 prices
Selected condition：
Brand
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 10MG
- 20mg
- 25MG
- 1mlx10mM(inDMSO)
- 50mg
- 100mg
- ManufacturerACHEMBLOCK
- Product numberU107019
- Product descriptionAilanthone 98.00%
- Packaging10MG
- Price$95
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU107019
- Product descriptionAilanthone 98.00%
- Packaging25MG
- Price$190
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberW1315
- Product descriptionAilanthone
- Packaging25mg
- Price$638
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0004878
- Product descriptionAILANTHONE 95.00%
- Packaging5MG
- Price$500.31
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN97561
- Product descriptionAilanthone ≥98%
- Packaging10mg
- Price$418
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS015012
- Product description(1R,2R,3aS,3a1S,6aR,7aS,11S,11aS,11bR)-1,2,11-Trihydroxy-8,11a-dimethyl-3-methylene-2,3,3a,4,7,7a,11,11a-octahydro-1H-1,3a1-(epoxymethano)dibenzo[de,g]chromene-5,10(6aH,11bH)-dione
- Packaging100mg
- Price$735
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2388
- Product descriptionAilanthone
- Packaging100mg
- Price$875
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number2388
- Product descriptionAilanthone
- Packaging10mg
- Price$175
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number2388
- Product descriptionAilanthone
- Packaging25mg
- Price$335
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number2388
- Product descriptionAilanthone
- Packaging5mg
- Price$95
- Updated2026-05-22
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1296130
- Product descriptionAilanthone 99.96%
- Packaging1mg
- Price$80
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1296130
- Product descriptionAilanthone 99.96%
- Packaging5mg
- Price$120
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1296130
- Product descriptionAilanthone 99.96%
- Packaging1mlx10mM(inDMSO)
- Price$130
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1296130
- Product descriptionAilanthone 99.96%
- Packaging10mg
- Price$160
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb593724
- Product descriptionAilanthone
- Packaging10mg
- Price$513.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb104670
- Product descriptionAilanthone >98%,Standard References Grade
- Packaging20mg
- Price$569.5
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | U107019 | Ailanthone 98.00% | 10MG | $95 | 2026-05-27 | Buy |
| ACHEMBLOCK | U107019 | Ailanthone 98.00% | 25MG | $190 | 2026-05-27 | Buy |
| AK Scientific | W1315 | Ailanthone | 25mg | $638 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0004878 | AILANTHONE 95.00% | 5MG | $500.31 | 2021-12-16 | Buy |
| Arctom | CFN97561 | Ailanthone ≥98% | 10mg | $418 | 2021-12-16 | Buy |
| Arctom | AS015012 | (1R,2R,3aS,3a1S,6aR,7aS,11S,11aS,11bR)-1,2,11-Trihydroxy-8,11a-dimethyl-3-methylene-2,3,3a,4,7,7a,11,11a-octahydro-1H-1,3a1-(epoxymethano)dibenzo[de,g]chromene-5,10(6aH,11bH)-dione | 100mg | $735 | 2021-12-16 | Buy |
| AvaChem | 2388 | Ailanthone | 100mg | $875 | 2026-05-22 | Buy |
| AvaChem | 2388 | Ailanthone | 10mg | $175 | 2026-05-22 | Buy |
| AvaChem | 2388 | Ailanthone | 25mg | $335 | 2026-05-22 | Buy |
| AvaChem | 2388 | Ailanthone | 5mg | $95 | 2026-05-22 | Buy |
| Biorbyt Ltd | orb1296130 | Ailanthone 99.96% | 1mg | $80 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1296130 | Ailanthone 99.96% | 5mg | $120 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1296130 | Ailanthone 99.96% | 1mlx10mM(inDMSO) | $130 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1296130 | Ailanthone 99.96% | 10mg | $160 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb593724 | Ailanthone | 10mg | $513.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb104670 | Ailanthone >98%,Standard References Grade | 20mg | $569.5 | 2021-12-16 | Buy |
Properties
Melting point :235-237 °C
Boiling point :641.0±55.0 °C(Predicted)
Density :1.47
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO:100.0(Max Conc. mg/mL);265.67(Max Conc. mM)
form :A crystalline solid
pka :11.85±0.70(Predicted)
color :White to off-white
InChIKey :WBBVXGHSWZIJST-BIKIFPNSNA-N
SMILES :[C@]123CO[C@@]4(O)[C@H](O)C(=C)C1CC(=O)O[C@]2([H])C[C@@]1([H])C(C)=CC(=O)[C@@H](O)[C@]1(C)[C@]34[H] |&1:0,3,5,14,17,24,26,28,r|
LogP :-0.760 (est)
Boiling point :641.0±55.0 °C(Predicted)
Density :1.47
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO:100.0(Max Conc. mg/mL);265.67(Max Conc. mM)
form :A crystalline solid
pka :11.85±0.70(Predicted)
color :White to off-white
InChIKey :WBBVXGHSWZIJST-BIKIFPNSNA-N
SMILES :[C@]123CO[C@@]4(O)[C@H](O)C(=C)C1CC(=O)O[C@]2([H])C[C@@]1([H])C(C)=CC(=O)[C@@H](O)[C@]1(C)[C@]34[H] |&1:0,3,5,14,17,24,26,28,r|
LogP :-0.760 (est)
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Ailanthone is a quassinoid that has been found in Ailanthus and has diverse biological activities. It is active against the P. falciparum strains HB-3 and Dd-2 in vitro (IC50s = 0.003 and 0.037 μg/ml, respectively). Ailanthone is phytotoxic, inhibiting radish seed germination by 88% when used at a concentration of 1 mM. It inhibits dihydrotestosterone-induced androgen receptor transcriptional activity (IC50 = 69 nM in a reporter assay), as well as the growth and colony formation of LNCaP and 22RV1 androgen receptor-expressing cells, but not androgen receptor-negative PC3 and DU145 cells, when used at a concentration of 0.1 μM. Ailanthone (2 mg/kg) reduces tumor volume in 22Rv1, LNCaP, and VCaP castration-resistant prostate cancer (CRPC) mouse xenograft models.More related product prices
Carboxyatractyloside Deacetyltaxol BETA-ELEMONIC ACID 10-Deacetylbaccatin IIIRelated product price
-
Carboxyatractyloside
$32-2137 -
Deacetyltaxol
$50-6425 -
BETA-ELEMONIC ACID
$12-1109
Suppliers and manufacturers
Chengdu Biopurify Phytochemicals Ltd.
BOC Sciences
Hefei TNJ Chemical Industry Co.,Ltd.
HANGZHOU LEAP CHEM CO., LTD.
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
ANHUI BYERSEN BIOTECH CO. LTD
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.
