Clascoterone
|
- $27 - $9435.2
- Product name: Clascoterone
- CAS: 19608-29-8
- MF: C24H34O5
- MW: 402.52
- EINECS:685-282-9
- MDL Number:MFCD18384978
- Synonyms:17alpha-propio17-(1-oxopropoxy)pregn-4-ene-3,20-dione;CB-03-01 17alpha-propionate;Cortexolone 17-alpha-propionate;17 alpha-propionate (CB-03-01);21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione;Clascoterone;CB-03-01;CORTEXOLONE 17Α-PROPIONATE;CORTEXOLONE 17 ALPHA-PROPIONATE;Pregn-4-ene-3,20-dione, 21-hydroxy-17-(1-oxopropoxy)-
41 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 0.25g
- 0.5g
- 500mg
- 1G
- 2g
- 50g
- Manufactureraablocks
- Product numberAA00ABDK
- Product description21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione ≥98%
- Packaging5mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABDK
- Product description21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione
- Packaging25mg
- Price$55
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABDK
- Product description21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione
- Packaging50mg
- Price$67
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABDK
- Product description21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione
- Packaging100mg
- Price$95
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number0382CT
- Product descriptionCortexolone17alpha-propionate
- Packaging25mg
- Price$235
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0382CT
- Product descriptionCortexolone17alpha-propionate
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007230
- Product descriptionCORTEXOLONE-17-ALPHA-PROPIONATE 95.00%
- Packaging10MG
- Price$1006.58
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007230
- Product descriptionCORTEXOLONE-17-ALPHA-PROPIONATE 95.00%
- Packaging50MG
- Price$1734.23
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007230
- Product descriptionCORTEXOLONE-17-ALPHA-PROPIONATE 95.00%
- Packaging1G
- Price$9435.2
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3108
- Product descriptionClascoterone
- Packaging500mg
- Price$500
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3108
- Product descriptionClascoterone
- Packaging100mg
- Price$175
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3108
- Product descriptionClascoterone
- Packaging50mg
- Price$110
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3108
- Product descriptionClascoterone
- Packaging10mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3108
- Product description17alpha-propionate
- Packaging5mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3108
- Product descriptionClascoterone
- Packaging25mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154679
- Product descriptionCB-03-01 >99%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ABDK | 21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione ≥98% | 5mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00ABDK | 21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione | 25mg | $55 | 2026-05-28 | Buy |
| aablocks | AA00ABDK | 21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione | 50mg | $67 | 2026-05-28 | Buy |
| aablocks | AA00ABDK | 21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione | 100mg | $95 | 2026-05-28 | Buy |
| AK Scientific | 0382CT | Cortexolone17alpha-propionate | 25mg | $235 | 2021-12-16 | Buy |
| AK Scientific | 0382CT | Cortexolone17alpha-propionate | 10mg | $160 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007230 | CORTEXOLONE-17-ALPHA-PROPIONATE 95.00% | 10MG | $1006.58 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007230 | CORTEXOLONE-17-ALPHA-PROPIONATE 95.00% | 50MG | $1734.23 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007230 | CORTEXOLONE-17-ALPHA-PROPIONATE 95.00% | 1G | $9435.2 | 2021-12-16 | Buy |
| ApexBio Technology | A3108 | Clascoterone | 500mg | $500 | 2026-05-06 | Buy |
| ApexBio Technology | A3108 | Clascoterone | 100mg | $175 | 2026-05-06 | Buy |
| ApexBio Technology | A3108 | Clascoterone | 50mg | $110 | 2026-05-06 | Buy |
| ApexBio Technology | A3108 | Clascoterone | 10mg | $50 | 2026-05-06 | Buy |
| ApexBio Technology | A3108 | 17alpha-propionate | 5mg | $142 | 2021-12-16 | Buy |
| ApexBio Technology | A3108 | Clascoterone | 25mg | $70 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb154679 | CB-03-01 >99% | 100mg | $615.4 | 2021-12-16 | Buy |
Properties
Boiling point :538.9±50.0 °C(Predicted)
Density :1.19
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Powder
pka :12.98±0.10(Predicted)
color :White to light yellow
InChIKey :GPNHMOZDMYNCPO-PDUMRIMRSA-N
SMILES :C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@](OC(=O)CC)(C(=O)CO)CC3)CC2
Density :1.19
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Powder
pka :12.98±0.10(Predicted)
color :White to light yellow
InChIKey :GPNHMOZDMYNCPO-PDUMRIMRSA-N
SMILES :C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@](OC(=O)CC)(C(=O)CO)CC3)CC2
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Clascoterone (Winlevi®) is an androgen receptor inhibitor being developed as a topical cream and solution by Cassiopea (a spin-out company of Cosmo Pharmaceuticals) for the treatment of androgen-dependent skin disorders, including androgenetic alopecia and acne vulgaris. Although the exact mechanism of action of clascoterone for the topical treatment of acne vulgaris is unknown, the drug is believed to compete with the androgen dihydrotestosterone for binding to androgen receptors in the sebaceous gland and hair follicles to attenuate signalling necessary for acne pathogenesis. In August 2020, clascoterone cream 1% received its first approval in the USA for the topical treatment of acne vulgaris in patients 12 years of age or older. Clinical studies of a different formulation of clascoterone (a solution containing a higher concentration of the drug) for the treatment of androgenetic alopecia are underway in Germany and the USA. This article summarizes the milestones in the development of clascoterone leading to this first approval for the topical treatment of acne vulgaris.Related product price
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