lifitegrast
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- $16 - $1400
- Product name: lifitegrast
- CAS: 1025967-78-5
- MF: C29H24Cl2N2O7S
- MW: 615.48
- EINECS:813-044-8
- MDL Number:MFCD28502439
- Synonyms:lifitegrast;Lifitegrast, SAR 1118;L-Phenylalanine,N-[[2-(6-benzofuranylcarbonyl)-5,7-dichloro-1,2,3,4-tetrahydro-6-isoquinolinyl]carbonyl]-3-(methylsulfonyl)-;N-[[2-(6-Benzofuranylcarbonyl)-5,7-dichloro-1,2,3,4-tetrahydro-6-isoquinolinyl]carbonyl]-3-(methylsulfonyl)-L-phenylalanine;SAR 1118;(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic;Lifitegrast（API）;SAR-1118;SAR1118
87 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Activate Scientific
- AK Scientific
- Alichem
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- Chemcia Scientific
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 2.5mg
- 10mM*1mLinDMSO(Solution)
- 1mg
- 10mM*1mLinDMSO
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 0.25G
- 250.00mg
- 250mg
- 500mg
- 1.00g
- 1g
- 3G
- 5g
- 5.00g
- Manufactureraablocks
- Product numberAA0007S2
- Product description(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97%
- Packaging1mg
- Price$16
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA0007S2
- Product description(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97%
- Packaging5mg
- Price$19
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA0007S2
- Product description(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 98%(HPLC)
- Packaging10mg
- Price$22
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA0007S2
- Product description(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97%
- Packaging25mg
- Price$23
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA0007S2
- Product description(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97%
- Packaging50mg
- Price$28
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA0007S2
- Product description(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97%
- Packaging100mg
- Price$34
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA0007S2
- Product description(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97%
- Packaging250mg
- Price$64
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA0007S2
- Product description(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97%
- Packaging1g
- Price$166
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA0007S2
- Product description(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97%
- Packaging5g
- Price$807
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberL18012
- Product descriptionLifitegrast 98%
- Packaging5G
- Price$1085
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberL18012
- Product descriptionLifitegrast 98%
- Packaging5G
- Price$1085
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL18012
- Product descriptionLifitegrast 98%
- Packaging1G
- Price$300
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberL18012
- Product descriptionLifitegrast 98%
- Packaging1G
- Price$300
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL18012
- Product descriptionLifitegrast 98%
- Packaging100MG
- Price$60
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberL18012
- Product descriptionLifitegrast 98%
- Packaging100MG
- Price$60
- Updated2026-05-27
- Buy
- ManufacturerActivate Scientific
- Product numberAS59476
- Product descriptionLifitegrast 95+%
- Packaging1mg
- Price$59
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0007S2 | (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97% | 1mg | $16 | 2026-05-25 | Buy |
| aablocks | AA0007S2 | (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97% | 5mg | $19 | 2026-05-25 | Buy |
| aablocks | AA0007S2 | (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 98%(HPLC) | 10mg | $22 | 2026-05-25 | Buy |
| aablocks | AA0007S2 | (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97% | 25mg | $23 | 2026-05-25 | Buy |
| aablocks | AA0007S2 | (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97% | 50mg | $28 | 2026-05-25 | Buy |
| aablocks | AA0007S2 | (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97% | 100mg | $34 | 2026-05-25 | Buy |
| aablocks | AA0007S2 | (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97% | 250mg | $64 | 2026-05-25 | Buy |
| aablocks | AA0007S2 | (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97% | 1g | $166 | 2026-05-25 | Buy |
| aablocks | AA0007S2 | (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 97% | 5g | $807 | 2026-05-25 | Buy |
| ACHEMBLOCK | L18012 | Lifitegrast 98% | 5G | $1085 | 2026-05-25 | Buy |
| ACHEMBLOCK | L18012 | Lifitegrast 98% | 5G | $1085 | 2026-05-27 | Buy |
| ACHEMBLOCK | L18012 | Lifitegrast 98% | 1G | $300 | 2026-05-25 | Buy |
| ACHEMBLOCK | L18012 | Lifitegrast 98% | 1G | $300 | 2026-05-27 | Buy |
| ACHEMBLOCK | L18012 | Lifitegrast 98% | 100MG | $60 | 2026-05-25 | Buy |
| ACHEMBLOCK | L18012 | Lifitegrast 98% | 100MG | $60 | 2026-05-27 | Buy |
| Activate Scientific | AS59476 | Lifitegrast 95+% | 1mg | $59 | 2021-12-16 | Buy |
Properties
Melting point :>163°C (dec.)
Boiling point :811.9±65.0 °C(Predicted)
Density :1.479±0.06 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Sonicated)
form :Solid
pka :3.14±0.10(Predicted)
color :White to Off-White
Stability :Hygroscopic
InChIKey :JFOZKMSJYSPYLN-QHCPKHFHSA-N
SMILES :C(O)(=O)[C@H](CC1=CC=CC(S(C)(=O)=O)=C1)NC(C1C(Cl)=CC2=C(C=1Cl)CCN(C(C1C=C3OC=CC3=CC=1)=O)C2)=O
Boiling point :811.9±65.0 °C(Predicted)
Density :1.479±0.06 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Sonicated)
form :Solid
pka :3.14±0.10(Predicted)
color :White to Off-White
Stability :Hygroscopic
InChIKey :JFOZKMSJYSPYLN-QHCPKHFHSA-N
SMILES :C(O)(=O)[C@H](CC1=CC=CC(S(C)(=O)=O)=C1)NC(C1C(Cl)=CC2=C(C=1Cl)CCN(C(C1C=C3OC=CC3=CC=1)=O)C2)=O
Safety Information
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Description
Lifitegrast (Xiidra; lifitegrast sodium; SAR1118; SHP606; SPD606) is a lymphocyte functionassociated antigen-1 (LFA-1) antagonist. It inhibits T-cell inflammation by blocking the binding of two key surface proteins (LFA-1 and ICAM-1) that mediate the chronic inflammatory cascade associated with dry eye disease. In a phase III clinical trial, lifitegrast 5% ophthalmic solution (50 mg/mL) is administered as a single 0.2mL eye drop twice a day into each eye for an 84 day treatment period.
Lifitegrast does not currently have Marketing Authorisation in the EU for any indication. Lifitegrast is licensed for use in the USA for treatment of the signs and symptoms of dry eye disease. The most common adverse reactions (incidence 5-25%) reported following the use of lifitegrast are instillation site irritation, dysgeusia, and decreased visual acuity.
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Suppliers and manufacturers
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Lifitegrast
CAS:1025967-78-5
