polymyxin B(1)
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- $120 - $759
- Product name: polymyxin B(1)
- CAS: 4135-11-9
- MF: C56H98N16O13
- MW: 1203.48
- EINECS:
- MDL Number:MFCD01699017
- Synonyms:polymyxin B(1);(-)-N2-[[(6S)-6-Methyloctanoyl]-L-A2bu-L-Thr-L-A2bu-]cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-);(6S)-N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide;polymyxin B1Q: What is polymyxin B1 Q: What is the CAS Number of polymyxin B1;(S)-N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-((R)-1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide;Polymyxin B1-[13C6,15N] TFA salt;Glucosamine Hydrochloride Impurity 33
6 prices
Selected condition:
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
Package
- 1MG
- 5MG
- 10mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0013125
- Product descriptionPOLYMYXIN B(1) 95.00%
- Packaging1MG
- Price$225.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0013125
- Product descriptionPOLYMYXIN B(1) 95.00%
- Packaging5MG
- Price$501.05
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14074
- Product descriptionPolymyxin B1 ≥95%
- Packaging1mg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14074
- Product descriptionPolymyxin B1 ≥95%
- Packaging5mg
- Price$477
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14074
- Product descriptionPolymyxin B1 ≥95%
- Packaging10mg
- Price$759
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0019929
- Product descriptionPolymyxinB1 ≥96.0%
- Packaging1mg
- Price$450
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0013125 | POLYMYXIN B(1) 95.00% | 1MG | $225.75 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0013125 | POLYMYXIN B(1) 95.00% | 5MG | $501.05 | 2021-12-16 | Buy |
Cayman Chemical | 14074 | Polymyxin B1 ≥95% | 1mg | $120 | 2024-03-01 | Buy |
Cayman Chemical | 14074 | Polymyxin B1 ≥95% | 5mg | $477 | 2024-03-01 | Buy |
Cayman Chemical | 14074 | Polymyxin B1 ≥95% | 10mg | $759 | 2024-03-01 | Buy |
ChemScene | CS-0019929 | PolymyxinB1 ≥96.0% | 1mg | $450 | 2021-12-16 | Buy |
Properties
Boiling point :838.79°C (rough estimate)
Density :1.0500 (rough estimate)
refractive index :1.6200 (estimate)
storage temp. :Store at -20°C
solubility :PBS (pH 7.2): 2 mg/ml
form :A crystalline solid
pka :13.08±0.70(Predicted)
color :White to off-white
Sequence :{Dab(6-methyl-1-oxooctyl)}-Thr-{Dab}-{Dab}-{Dab}-{d-Phe}-Leu-{Dab}-{Dab}-Thr (Lactam bridge: Dab4-Thr10)
InChIKey :WQVJHHACXVLGBL-CTMZAJDNSA-N
Density :1.0500 (rough estimate)
refractive index :1.6200 (estimate)
storage temp. :Store at -20°C
solubility :PBS (pH 7.2): 2 mg/ml
form :A crystalline solid
pka :13.08±0.70(Predicted)
color :White to off-white
Sequence :{Dab(6-methyl-1-oxooctyl)}-Thr-{Dab}-{Dab}-{Dab}-{d-Phe}-Leu-{Dab}-{Dab}-Thr (Lactam bridge: Dab4-Thr10)
InChIKey :WQVJHHACXVLGBL-CTMZAJDNSA-N
Safety Information
Symbol(GHS): |
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Description
The polymyxins are cationic peptides originally isolated from B. polymyxa. They bind and kill Gram-negative bacteria. The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B1 is a form of polymyxin B which terminates with 6-methyloctanamide. Polymyxin B1 is comparable to other B polymyxins in its ability to kill P. aeruginosa, A. baumannii, and K. pneumoniae isolates. Its relative pharmacokinetics and nephrotoxicity have not been examined.Related product price
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