Dexamethasone 21-phosphate disodium salt
| | 2392-39-4 Basic information More.. |
| Product Name: | Dexamethasone 21-phosphate disodium salt | | Synonyms: | dexadreson;dexagro;dexamethasonedisodiumphosphate;disodiumdexamethasonephosphate;disodiumsalt,(11beta,16alpha)-y);DEXAMETHASONE 21-PHOSPHATE DISODIUM SALT;DEXAMETHASONE PHOSPHATE DISODIUM SALT;dexamethasone 21-(disodium phosphate) | | CAS: | 2392-39-4 | | MF: | C22H28FNa2O8P | | MW: | 516.4 | | EINECS: | 219-243-0 | | Mol File: | 2392-39-4.mol |  |
Use
Dexamethasone 21-phosphate disodium salt is a system glucocorticoid with anti-inflammatory properties, is the pro-drug which is converted to dexamethasone in vivo. It stimulates uptake of glutamine in the cerebral cortex and induces apoptosis. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways.
It is freely soluble in water, slightly soluble in ethanol, and insoluble in chloroform and in ether. It is an inhibitor of the sodium phosphate symporter and GR activator.
Additionally, it serves as an activator of food, medicine, glucocorticoid and anti inflammatory.
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2392-39-4
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