34493-98-6 Basic information More..
Product Name:(2R,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy-2-hydroxy-cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
Synonyms:DIBEKACIN;(2R,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy-2-hydroxy-cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol;6-O-(3-Amino-3-deoxy-α-D-glucopyranosyl)-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-2-deoxy-D-streptamine;Aids070753;Aids-070753;Brn 1441606;D-Streptamine, o-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-o-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl)-(1-4)-2-deoxy-;O-3-AMino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diaMino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1→4)]-2-deoxy-D-streptaMine
CAS:34493-98-6
MF:C18H37N5O8
MW:451.52
EINECS:252-064-6
Mol File:34493-98-6.mol
34493-98-6

Use

3′,4′-dideoxy kanamycin b. a semisynthetic aminoglycoside closely related to the natural compound tobramycin (3′-deoxy kanamycin b). supplied as the sulfate. it is active against staphylococci including methicillinresistant strains, a wide range of enterobacteria, acinetobacter and pseudomonas spp. it is also active against m. tuberculosis and the m. avium complex (mics 4–16 mg/l). it exhibits the usual aminoglycoside properties of bactericidal activity at concentrations close to the mic and bactericidal synergy with selected β-lactam antibiotics.

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