| | 849217-64-7 Basic information More.. |
| Product Name: | Foretinib (GSK1363089) | | Synonyms: | GSK 1363089;N-[3-Fluoro-4-[[6-(methyloxy)-7-[[3-(morpholin-4-yl)propyl]oxy]quinolin-4-yl]oxy]phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide;XL-880,Foretinib;XL880(GSK1363089);FORETINIB GLAXOSMITHKLINE PAPILLARY RENAL CELL CARCINOMA PHASE IIRSCH. TRIANGLE PARK, NC (SEE ALSO HEAD/NECK) (888) 825-5249;foretinib
N1-{3-fluoro-4-[(6-(Methyloxy)-7-{[3-(4-Morpholinyl)propyl]oxy}-4-quinolinyl)oxy]phenyl}-N1'-(4-fluorophenyl)-1,1-cyclopropanedicarboxaMide;Foretinib (GSK1363089, XL880) | | CAS: | 849217-64-7 | | MF: | C34H34F2N4O6 | | MW: | 632.65 | | EINECS: | | | Mol File: | 849217-64-7.mol |  |
Use
Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit, PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
- Foretinib (GSK1363089)
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- US $0.00-0.00 / KG
- 2022-10-14
- CAS:849217-64-7
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1Ton
- Foretinib (GSK1363089)
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- US $2.00 / kg
- 2019-07-06
- CAS:849217-64-7
- Min. Order: 1 kg
- Purity: 99%
- Supply Ability: 100kg
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849217-64-7
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