| | 1421373-65-0 Basic information More.. |
| Product Name: | AZD-9291 | | Synonyms: | N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide;Mereletinib mesylate(AZD9291);AZD9291 (free base);Osimertinib (AZD-9291);AZD9291, Osimertinib;AZD9291 Base;Osimertinib Base;AZD9291 10G | | CAS: | 1421373-65-0 | | MF: | C28H33N7O2 | | MW: | 499.61 | | EINECS: | 629-848-5 | | Mol File: | 1421373-65-0.mol |  |
Use
AZD-9291 (Mesylate), also known as Osimertinib, belongs to a third-generation EGFR (epidermal growth factor receptor) inhibitor. It can be used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) in case when the cancer cells carry specific mutations (such as T790M) in the epidermal growth factor receptor. It takes effect through directly binding to the certain mutant forms of EGFR (T790M, L858R, and exon 19 deletions) that are frequently found in NSCLC, further causing poor prognosis for late-stage disease. Since it spares wild type EGFR during therapy, it has only limited toxicity.
- AZD-9291
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- US $5.00-0.10 / KG
- 2024-04-09
- CAS:1421373-65-0
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: g-kg-tons, free sample is available
- Osimertinib (AZD9291)
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- US $0.00 / g
- 2024-03-12
- CAS:1421373-65-0
- Min. Order: 1g
- Purity: 98% HPLC
- Supply Ability: 1KG
- AZD-9291
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- US $0.00 / g
- 2023-11-27
- CAS:1421373-65-0
- Min. Order: 10g
- Purity: 99%
- Supply Ability: 50kg
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1421373-65-0
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