| | 144490-63-1 Basic information More.. |
| Product Name: | 19-Epi FK-506 | | Synonyms: | 19-Epi FK-506;QJJXYPPXXYFBGM-VIJOMOBOSA-N;tacrolimus difference SECRETARY 19 epimers;ascomycin epimeric 19 body;Ascomycin 19 epimer;Tacrolimus Impurity 8（Tacrolimus EP Impurity G）（Tacrolimus 19-Epimer）;Tacrolimus Impurity 6;19-Epi FK-506 (Tacrolimus Impurity) | | CAS: | 144490-63-1 | | MF: | C44H69NO12 | | MW: | 804.03 | | EINECS: | | | Mol File: | 144490-63-1.mol |  |
Use
19-Epi FK-506 is an impurity in the synthesis of FK-506 [Tacrolimus] (F370000), an immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.
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144490-63-1
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