Ethyl (hydroxyimino)cyanoacetate potassium salt
| | 158014-03-0 Basic information More.. |
| Product Name: | Ethyl (hydroxyimino)cyanoacetate potassium salt | | Synonyms: | 2-Cyano-2-(hydroxyimino)acetic acid ethyl ester, potassium salt;Ethyl (hydroxyimino)cyanoacetate potassium salt;K-Oxyma;Cyano(hydroxyimino)acetic acid ethyl ester potassium salt;2-Cyano-2-(hydroxyimino)acetic acid ethyl ester potassium salt (1:1);Ethyl (hydroxyimino)cyanoacetate potassium;K-Oxyma≥ 99% (HPLC);K-Oxyma Pure Novabiochem | | CAS: | 158014-03-0 | | MF: | C5H5KN2O3 | | MW: | 180.2031 | | EINECS: | | | Mol File: | 158014-03-0.mol |  |
Use
Ethyl (hydroxyimino)cyanoacetate potassium salt is a Non-explosive replacement for HOBt and HOAt with at least comparable performance to HOAt Outperforms HOAt in sterically demanding peptide bond formations Compatible with carbodiimide-mediated; solution and solid phase peptide coupling; Less epimerization than HOBt in fragment condensation reactions K-salt especially useful in peptide coupling on mild acid-labile resins such as 2-chlorotrityl; leading to minimal to no cleavage of the peptide from the resin due to its more alkaline character K-salt has a higher melting point than OxymaPure.
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158014-03-0
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158014-03-0
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