| | 10179-57-4 Basic information More.. |
| Product Name: | MLS-573151 | | Synonyms: | MLS-573151;Benzenesulfonamide, 4-(4,5-dihydro-3,5-diphenyl-1H-pyrazol-1-yl)-;4-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide;MLS-573151,granulocytes,Inhibitor,Ras,inhibit,MLS-000573151,MLS 000573151,GTPase,MLS 573151,Cdc42,MLS573151,MLS000573151 | | CAS: | 10179-57-4 | | MF: | C21H19N3O2S | | MW: | 377.46 | | EINECS: | | | Mol File: | 10179-57-4.mol |  |
Use
The Rho family of GTPases regulates diverse signal transduction pathways. One member, the cell division control protein 42 homolog (Cdc42), is involved in filopodia function, cell polarity, cell cycling, and other processes. MLS-573151 is a specific, cell permeable inhibitor of Cdc42 (IC50 = 2 μM). It has no effect on other GTPases, including the related Rho family members RhoA, Rac1, and Rac2. It acts by blocking the binding of GTP to Cdc42.[Cayman Chemical]
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10179-57-4
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