186692-46-6 Basic information More..
Product Name:Roscovitine
Synonyms:2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol, 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine;(2R)-2-[[6-(benzylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol;2-(R)-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE;2-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE;6-BENZYLAMINO-2-(R)-[(1-ETHYL)-2-HYDROXYETHYLAMINO]-9-ISOPROPYLPURINE;ROSCOVITINE;(R)-ROSCOVITINE;(R)-2-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE
CAS:186692-46-6
MF:C19H26N6O
MW:354.45
EINECS:
Mol File:186692-46-6.mol
186692-46-6

Use

Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). Roscovitine has been found to produce apoptosis in treated cancerous cells of non-small cell lung cancer (NSCLC) and other cancers. Studies show that Roscovitine displays increased anti-mitotic activity at the G1/S and G2/M phases of the cell cycle. Roscovitine maybe useful in the treatment of non-small cell lung c ancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation disorders.

Roscovitine manufacturers

  • ROSCOVITINE
  • US $50.00 / kg
  • 2023-03-24
  • CAS:186692-46-6
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 20 tons
  • ROSCOVITINE
  • US $15.00-10.00 / KG
  • 2021-08-12
  • CAS:186692-46-6
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • ROSCOVITINE
  • US $1.00 / KG
  • 2019-09-06
  • CAS:186692-46-6
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 20kg
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