| | 49842-07-1 Basic information More.. |
| Product Name: | Tobramycin sulfate | | Synonyms: | TOBRAMYCIN SULFATE SALT;TOBRAMYCIN SULPHATE;1-epitobramycinsulfate;d-6-trideoxy-alpha-d-ribohexopyranosyl-(1-4))-2-deoxysulfate(salt);obracine;streptamine,o-3-amino-3-deoxy-alpha-d-glucopyranosyl-(1-6)-o-(2,6-diamino-2,3,;tenemicin;O-[3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1→4)]-2-deoxy-D-streptamine sulfate | | CAS: | 49842-07-1 | | MF: | C18H39N5O13S | | MW: | 565.59 | | EINECS: | 256-499-2 | | Mol File: | 49842-07-1.mol |  |
Use
Introduced in 1976, tobramycin sulfate (Nebcin) is the mostactive of the chemically related aminoglycosides called nebramycinsobtained from a strain of Streptomyces tenebrarius Five members of the nebramycin complex have beenidentified chemically.Factors 4 and 4＇ are 6＂-O-carbamoylkanamycin B andkanamycin B, respectively; factors 5＇ and 6 are 6＂-O-carbamoyltobramycinand tobramycin; and factor 2 isapramycin, a tetracyclic aminoglycoside with an unusual bicycliccentral ring structure. Kanamycin B and tobramycinprobably do not occur in fermentation broths per se but areformed by hydrolysis of the 6-O＂-carbamoyl derivatives inthe isolation procedure.The most important property of tobramycin is its activityagainst most strains of P. aeruginosa, exceeding that of gentamicinby twofold to fourfold. Some gentamicin-resistantstrains of this troublesome organism are sensitive to tobramycin,but others are resistant to both antibiotics. OtherGram-negative bacilli and staphylococci are generally moresensitive to gentamicin. Tobramycin more closely resembleskanamycin B in structure (it is 3＇-deoxykanamycin B).
- Tobramycin sulfate
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- US $1.00 / kg
- 2023-04-12
- CAS:49842-07-1
- Min. Order: 1kg
- Purity: 99.74% HPLC
- Supply Ability: 5000tons/year
- Tobramycin sulfate
-
- US $1.00-1.00 / KG
- 2021-07-20
- CAS:49842-07-1
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 50tons
- Tobramycin sulfate
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- US $1.00 / KG
- 2020-01-03
- CAS:49842-07-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10000KGS
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49842-07-1
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