| | 60-70-8 Basic information More.. |
| Product Name: | veratramine | | Synonyms: | veratramine;Vreaframine;(3b,23b)-14,15,16,17-Teradehydroveratraman-3,23-diol;NSC 17821;NSC 2388;AIDS011940;(3,23)-14,15,16,17-Teradehydroveratraman-3,23-diol;NSC 23880 | | CAS: | 60-70-8 | | MF: | C27H39NO2 | | MW: | 409.6 | | EINECS: | | | Mol File: | 60-70-8.mol |  |
Use
The hedgehog (Hh) signaling pathway, which is blocked by cyclopamine , plays a key role in morphogenesis and has potential applications in the treatment of cancer. Veratramine, a teratogenic steroidal alkaloid isolated from the corn lily (Veratrum sp.), is an analog of cyclopamine that can inhibit the Hh signaling-dependent proliferation of NIH/3T3 cells at 8 μM. Additionally, veratramine has anti-thrombotic activity as it dose dependently inhibits platelet aggregation in rabbits ex vivo. While it may be most useful as a signal transduction inhibitor for treating tumors, veratramine also induces serotonin release and inhibits its re-uptake in the CNS.
- veratramine
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- US $0.00 / MG
- 2024-04-28
- CAS:60-70-8
- Min. Order: 10MG
- Purity: 98% HPLC
- Supply Ability: 1000KG
- Veratramine
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- US $0.00 / mg
- 2023-02-24
- CAS:60-70-8
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- Veratramine 60-70-8
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- US $45.00 / g
- 2022-02-14
- CAS:60-70-8
- Min. Order: 10mg
- Purity: ≥98% HPLC
- Supply Ability: 1000.00 kgs
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60-70-8
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Product Name:(2S,3R,5S)-2-[(1S)-1-[(3S,6aR,11aS,11bR)-3-hydroxy-10,11b-dimethyl-1,2,3,4,6,6a,11,11a-octahydrobenzo[a]fluoren-9-yl]ethyl]-5-methylpiperidin-3-ol
CAS:60-70-8
Purity:95% Package:100g; 1kg Remarks:LN01327457 |
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