| | 389-08-2 Basic information More.. |
| Product Name: | Nalidixic acid | | Synonyms: | uroman;uroneg;uropan;Win18,320;Wintomylon;Nalidixic acid, Antibiotic for Culture Media Use Only;Nalidixic acid, 1,4-Dihydro-1-ethyl-7-methyl-1,8-naphthyridin-4-one-3-carboxylic acid;1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8 | | CAS: | 389-08-2 | | MF: | C12H12N2O3 | | MW: | 232.24 | | EINECS: | 206-864-7 | | Mol File: | 389-08-2.mol |  |
Use
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (NegGram) occurs as a pale buff crystalline powder that is sparingly soluble in water and ether but solublein most polar organic solvents.Nalidixic acid is useful in the treatment of urinary tractinfections in which Gram-negative bacteria predominate.The activity against indole-positive Proteus spp. is particularlynoteworthy, and nalidixic acid and its congeners representimportant alternatives for the treatment of urinary tractinfections caused by strains of these bacteria resistant toother agents. Nalidixic acid is rapidly absorbed, extensivelymetabolized, and rapidly excreted after oral administration.The 7-hydroxymethyl metabolite is significantly more activethan the parent compound. Further metabolism of theactive metabolite to inactive glucuronide and 7-carboxylicacid metabolites also occurs. Nalidixic acid possesses at1/2elim of 6 to 7 hours. It is eliminated, in part, unchanged inthe urine and 80% as metabolites.
- Nalidixic acid
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- US $0.00 / kg
- 2023-10-07
- CAS:389-08-2
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 20 tons
- Nalidixic acid
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- US $20.00 / kg
- 2022-08-17
- CAS:389-08-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000 Ton
- Nalidixic acid
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- US $15.00-10.00 / KG
- 2021-08-12
- CAS:389-08-2
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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389-08-2
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