| | 936563-96-1 Basic information More.. |
| Product Name: | Ibrutinib | | Synonyms: | According to Lu imatinib;2-Propen-1-one, 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-;PCI-32765 (Ibrutinib);IBRUTINIB;1-[(3R)-3-[4-AMino-3-(4-phenoxyphenyl)pyrazolo[3, 4-d]pyriMidin-1-yl]piperidin-1-yl]prop-2-en-1-one;1-{3-[4-Amino-3-(4-phenoxy-phenyl)-pyrazolo[3,4-d]pyrimidin-1-yl]-piperidin-1-yl}-but-3-en-1-one;1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one Ibrutinib (PCI32765);PCI-32765 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one | | CAS: | 936563-96-1 | | MF: | C25H24N6O2 | | MW: | 440.5 | | EINECS: | 805-642-2 | | Mol File: | 936563-96-1.mol |  |
Use
ibrutinib is a kind of bruton tyrosine kinase (btk) inhibitor, it could be used for the treatment of chronic lymphocytic leukemia (cll) and mantle cell lymphoma (mcl). Ibrutinib is a potent inhibitor of BTK that binds covalently to Cys-481 in the active site of BTK, resulting in inhibition of kinase activity. Ibrutinib does have significant activity against 19 other kinases, including seven with a cognate cysteine residue. These include BLK, BMX, ITK, TEC, EGFR, ERBB2, and JAK3.
- Ibrutinib
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- US $1.00 / g
- 2024-04-23
- CAS:936563-96-1
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100kg
- Ibrutinib
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- US $30.00-10.00 / kg
- 2024-04-22
- CAS:936563-96-1
- Min. Order: 1kg
- Purity: 99.9%
- Supply Ability: 500
- Ibrutinib
-
- US $30.00 / kg
- 2024-04-22
- CAS:936563-96-1
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 2000kg
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936563-96-1
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