442632-72-6 Basic information More..
Product Name:CK-636
Synonyms:CK-636;N-(2-(2-METHYL-1H-INDOL-3-YL)ETHYL)THIOPHENE-2-CARBOXAMIDE;N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide;CK-636, >=98%;CK-0944636;CK-636 N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide;N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide CK636;CK-636;CK636; CK 636
CAS:442632-72-6
MF:C16H16N2OS
MW:284.38
EINECS:200-256-5
Mol File:442632-72-6.mol
442632-72-6

Use

CK-636 inhibits actin polymerization mediated by Arp2/3 complex in live cells, and reduces the formation of actin filament comet tails by Listeria in infected SKOV3 cells. CK-636 inhibits lamellipodia formation at the leading edges of migrating T cells, and causes reduced velocity. In addition, a substantial fraction of CK-636-treated T cells on zigzag patterns with an acute turning angle are trapped near the interfaces formed by the turning points of zigzag patterns.

CK-636 manufacturers

  • CK-636
  • US $5.00 / KG
  • 2019-09-04
  • CAS:442632-72-6
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 1ton
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