134678-17-4 Basic information More..
Product Name:Lamivudine
Synonyms:LaMivudine(Epivir);3TC (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine;LaMivudine-13C-d2;3TC/Epivir-HBV;4-AMino-1-((2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl)pyriMidin-2(1H)-one;cis-Lamivudine;(-)-BCH-189;(-)-BETA-L-2',3'-DIDEOXY-3'-THIACYTIDINE
CAS:134678-17-4
MF:C8H11N3O3S
MW:229.26
EINECS:603-844-3
Mol File:134678-17-4.mol
134678-17-4

Use

Lamivudine is the (–) enantiomer of a cytidine analogue with sulfur substituted for the 3'carbon atom in the furanose ring [(–) 2',3'-dideoxy, 3'-thiacytidine]. It has significant activity in vitro against both HIV-1 and HIV-2 as well as HBV. Lamivudine is phosphorylated to the triphosphate metabolite by cellular kinases. The triphosphate derivative is a competitive inhibitor of the viral reverse transcriptase.

Lamivudine manufacturers

  • Lamivudine
  • US $185.00-65.00 / Kg/Bag
  • 2024-04-22
  • CAS:134678-17-4
  • Min. Order: 1Kg/Bag
  • Purity: 99% up, USP
  • Supply Ability: 20 tons
  • Lamivudine
  • US $0.00 / kg
  • 2024-04-08
  • CAS:134678-17-4
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 20tons
  • Lamivudine
  • US $35.00-25.00 / kg
  • 2024-03-16
  • CAS:134678-17-4
  • Min. Order: 1kg
  • Purity: 99.8%
  • Supply Ability: 200tons/year
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