Sulbactam

Use

Sulbactam is penicillanic acid sulfone or 1,1-dioxopenicillanicacid. This synthetic penicillin derivative is a potent inhibitorof S. aureus β-lactamase as well as many β-lactamaseselaborated by Gram-negative bacilli. Sulbactam has weak intrinsicantibacterial activity but potentiates the activity ofampicillin and carbenicillin against β-lactamase–producingS. aureus and members of the Enterobacteriaceae family. Itdoes not, however, synergize with either carbenicillin or ticarcillinagainst P. aeruginosa strains resistant to these agents.Failure of sulbactam to penetrate the cell envelope is a possibleexplanation for the lack of synergy.Fixed-dose combinations of ampicillin sodium and sulbactamsodium, marketed under the trade name Unasyn assterile powders for injection, have been approved for use inthe United States. These combinations are recommended forthe treatment of skin, tissue, intra-abdominal, and gynecologicalinfections caused by β-lactamase–producing strainsof S. aureus, E. coli, Klebsiella spp., P. mirabilis, B. fragilis,and Enterobacter and Acinetobacter spp.

Sulbactam manufacturers

• Sulbactam
• 
• US $8.00-1.00 / kg
• 2024-03-29
• CAS:68373-14-8
• Min. Order: 1kg
• Purity: 99%
• Supply Ability: g-kg-tons, free sample is available

• sulbactam
• 
• US $0.00-0.00 / Kg
• 2024-03-29
• CAS:68373-14-8
• Min. Order: 1Kg
• Purity: 99.9%
• Supply Ability: 200tons

• Sulbactam
• 
• US $0.00 / kg
• 2023-11-20
• CAS:68373-14-8
• Min. Order: 1kg
• Purity: 0.99
• Supply Ability: 20 tons