148-79-8 Basic information More..
Product Name:Thiabendazole
Synonyms:thibenzole200;thibenzoleatt;Thiprazole;Tiabenda;Tibimix 20;Tobaz;Top form wormer;topformwormer
CAS:148-79-8
MF:C10H7N3S
MW:201.25
EINECS:205-725-8
Mol File:148-79-8.mol
148-79-8

Use

2-(4-Thiazolyl)benzimidazole (Mintezol) occurs as a whitecrystalline substance that is only slightly soluble in waterbut is soluble in strong mineral acids. Thiabendazole is abasic compound with a pKa of 4.7 that forms complexeswith metal ions.Thiabendazole inhibits the helminth-specific enzymefumarate reductase. It is not known whether metal ionsare involved or if the inhibition of the enzyme is related tothiabendazole’s anthelmintic effect. Benzimidazole anthelminticdrugs such as thiabendazole and mebendazolealso arrest nematode cell division in metaphase by interferingwith microtubule assembly. They exhibit a highaffinity for tubulin, the precursor protein for microtubulesynthesis.Thiabendazole has broad-spectrum anthelmintic activity.It is used to treat enterobiasis, strongyloidiasis (threadworminfection), ascariasis, uncinariasis (hookworm infection), andtrichuriasis (whipworm infection). It has also been used torelieve symptoms associated with cutaneous larva migrans(creeping eruption) and the invasive phase of trichinosis. Inaddition to its use in human medicine, thiabendazole iswidely used in veterinary practice to control intestinalhelminths in livestock.

Thiabendazole manufacturers

  • thiabendazole
  • US $0.00-0.00 / Kg
  • 2024-04-09
  • CAS:148-79-8
  • Min. Order: 1Kg
  • Purity: 99.9%
  • Supply Ability: 200tons
  • Thiabendazole
  • US $0.00 / KG
  • 2024-04-08
  • CAS:148-79-8
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 20 TONS
  • Thiabendazole
  • US $0.00 / kg
  • 2023-09-26
  • CAS:148-79-8
  • Min. Order: 1kg
  • Purity: 98.00%
  • Supply Ability: 20tons
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