| | 127779-20-8 Basic information More.. |
| Product Name: | Saquinavir | | Synonyms: | (3S)-N-tert-Butyl-2-[(2R,3S)-3-[N-(2-quinolinylcarbonyl)-3-carbamoylalanylamino]-2-hydroxy-4-phenylbutyl]-1,2,3,4,4aβ,5,6,7,8,8aβ-decahydroisoquinoline-3α-carboxamide;(4aS,8aβ)-N-tert-Butyldecahydro-2-[(2R,3S)-2-hydroxy-4-phenyl-3-[[(2S)-3-carbamoyl-2-(2-quinolinylcarbonylamino)propanoyl]amino]butyl]isoquinoline-3α-carboxamide;Saquinavir & Saquinavir Mesylate;ButanediaMide,N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-diMethylethyl)aMino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylMethyl)propyl]-2-[(2-quinolinylcarbonyl)aMino]-,(2S)-;2-[[2-METHYL-3-(TRIFLUOROMETHYL)PHENYL]AMINO]PYRIDINE-3-CARBOXYLIC ACID;(2S)-N-[(2S,3R)-4-[(3S,4AS,8AS)-3-(TERT-BUTYLCARBAMOYL)-3,4,4A,5,6,7,8,8A-OCTAHYDRO-1H-ISOQUINOLIN-2-YL]-3-HYDROXY-1-PHENYL-BUTAN-2-YL]-2-(QUINOLINE-2-CARBONYLAMINO)BUTANEDIAMIDE;FLUNIXINE;SAGUINAVIR | | CAS: | 127779-20-8 | | MF: | C38H50N6O5 | | MW: | 670.84 | | EINECS: | 1806241-263-5 | | Mol File: | 127779-20-8.mol |  |
Use
Saquinavir mesylate, the first HIV protease inhibitor to reach the market, was
launched in the U.S.A.. It is indicated for use in combination with approved
nucleoside analogs for the treatment of advanced HIV infection. Saquinavir, a
transition state analog of Phe-Pro, is a very potent and competitive inhibitor of HIV-1
and HIV-2 proteases with high specificity. Saquinavir inhibits the last stage in the
replication process of HIV and prevents virion maturation in both acute and chronically
infected cells. Combination of saquinavir with the nucleoside analogs such as
zidovudine (AZT) or/and zalcitabine which inhibit the enzyme reverse transcriptase and
target at an earlier stage in the HIV replication process, shows a greater than additive
effect in increase in CD4 cell counts and reduction in viral load, with the combination
delaying the onset of resistance to either drug alone. Saquinavir is well tolerated alone
and in combination with A n .
- Saquinavir USP/EP/BP
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- US $1.10 / g
- 2021-07-16
- CAS:127779-20-8
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
- Saquinavir
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- US $15.00-10.00 / KG
- 2021-07-13
- CAS:127779-20-8
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Saquinavir
-
- US $15.00-10.00 / KG
- 2021-07-10
- CAS:127779-20-8
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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127779-20-8
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