28657-80-9 Basic information More..
Product Name:CINOXACIN
Synonyms:Cinoxacino;Cinoxacinum;CINOXACIN;TIMTEC-BB SBB003082;1-ethyl-6,7-methylenedioxy-4(1h)-oxocinnoline-3-carboxylicacid;3)dioxolo(4,5-g)cinnoline-3-carboxylicacid,1,4-dihydro-1-ethyl-4-oxo-(;1-ETHYL-1,4-DIHYDRO-4-OXO[1,3]DIOXOLO[4,5-G]CINNOLINE-3-CARBOXYLIC ACID;Cinoxacin (200 mg)
CAS:28657-80-9
MF:C12H10N2O5
MW:262.22
EINECS:249-133-8
Mol File:28657-80-9.mol
28657-80-9

Use

1-Ethyl-1,4-dihydro-4-oxo[1,3]dioxolo[4,5g]cinnoline-3-carboxylic acid (Cinobac) is a close congener (isostere) ofoxolinic acid (no longer marketed in the United States) andhas antibacterial properties similar to those of nalidixic andoxolinic acids. It is recommended for the treatment of urinary tract infectionscaused by strains of Gram-negative bacteria susceptibleto these agents. Early clinical studies indicate that thedrug possesses pharmacokinetic properties superior to thoseof either of its predecessors. Thus, following oral administration,higher urinary concentrations of cinoxacin thanof nalidixic acid or oxolinic acid are achieved. Cinoxacinappears to be more completely absorbed and less proteinbound than nalidixic acid.

CINOXACIN manufacturers

  • CINOXACIN USP/EP/BP
  • US $1.10 / g
  • 2021-07-20
  • CAS:28657-80-9
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons min
  • Cinoxacin
  • US $0.01-1.00 / KG
  • 2020-05-13
  • CAS:28657-80-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 50 tons
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CAS:28657-80-9
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