| 1616391-87-7 Basic information More.. |
Product Name: | GSK591 | Synonyms: | GSK591 (EPZ-015866);EPZ015866;GSK591(EPZ015866,GSK3203591);EPZ015866(GSK591);EPZ015866,GSK3203591;GSK591;GSK3203591(EPZ015866);EPZ-015866;EPZ 015866;GSK-591;GSK 591;GSK3203591;GSK-3203591;GSK 3203591 | CAS: | 1616391-87-7 | MF: | C22H28N4O2 | MW: | 380.48 | EINECS: | | Mol File: | 1616391-87-7.mol | |
Use
GSK591 is a chemical probe of PRMT5 (protein arginine methyltransferase 5), which plays a key role in various biological processes. PRMT5 is related to many human diseases including certain cancers like mantle cell lymphoma (MCL). Therefore, GSK591 is a useful tool for testing biological and therapeutic hypotheses. Study has shown that it can potential inhibit the PRMT5/MEP50 complex and symmetric arginine methylation of SMD3.
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1616391-87-7
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