Use
tridihexethyl chloride is useful for adjunctive therapy in a wide varietyof GI diseases, such as peptic ulcer, gastric hyperacidity,and hypermotility and spastic conditions, such as spasticcolon, functional diarrhea, pylorospasm, and other relatedconditions. Because its action is predominantly antisecretory,it is more effective in gastric hypersecretion than in hypermotilityand spasm. It is best administered intravenouslyfor the latter conditions. The side effects usually found with effective anticholinergictherapy occur with the use of this drug. These are drynessof mouth, mydriasis, and such. As with other anticholinergics,care should be exercised when administering the drug topatients with glaucomatous conditions, cardiac decompensation,and coronary insufficiency. It is contraindicated inpatients with obstruction at the bladder neck, prostatic hypertrophy,stenosing gastric and duodenal ulcers, or pyloric orduodenal obstruction.