192725-17-0 Basic information More..
Product Name:Lopinavir
Synonyms:LOPINAVIR;A 157378.0;ABT 378;Aluviran;Koletr;(aS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-Pyrimidineacetamide;Koletra;(2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
CAS:192725-17-0
MF:C37H48N4O5
MW:628.81
EINECS:200-001-8
Mol File:192725-17-0.mol
192725-17-0

Use

Lopinavir, the sixth HIV protease inhibitor in the “navir” class, was launched in coformulation with ritonavir, another HIV protease inhibitor already marketed (Abbott, 1996); this original formulation was introduced as Kaletra for use in combination with either nucleoside or non-nucleoside reverse transcriptase inhibitors for the treatment of AIDS in adults and children. Lopinavir is a peptidomimetic compound with a structural core identical to that of ritonavir, on which terminal groups, particularly a modified valine, were introduced by peptide coupling procedures. Lopinavir is a potent competitive inhibitor of HIV-I protease exhibiting high potential against ritonavir-resistant mutations.

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  • Lopinavir
  • 2025-07-12
  • CAS:192725-17-0
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  • 2025-07-11
  • CAS:192725-17-0
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  • Lopinavir
  • US $50.00 / KG
  • 2025-07-07
  • CAS:192725-17-0
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 20tons
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