| | 103628-46-2 Basic information More.. |
| Product Name: | Sumatriptan | | Synonyms: | 3-[2-(DIMETHYLAMINO)ETHYL]-N-METHYL-1H-INDOLE-5-METHANESULFONAMIDE, SUCCINATE;IMIGRAN;IMITREX;(3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide;3-(2-(dimethylamino)ethyl)-n-methyl-1h-indole-5-methanesulfonamid;3-[2-(Dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide;gr43175;gr43175x | | CAS: | 103628-46-2 | | MF: | C14H21N3O2S | | MW: | 295.4 | | EINECS: | | | Mol File: | 103628-46-2.mol |  |
Use
Sumatriptan was the first triptan approved (1991) for theacute treatment of migraine headaches. It has the lowestoral bioavailability among all triptans because of its lowlipophilicity. The availability of many different dosageforms (i.e., an oral tablet, a SC injection, a nasal spray formulation,and a suppository) allows the flexibility of tailoringtherapy to the needs of the individual patients, thusmaking sumatriptans a very useful drug for an acute treatmentof migraine headaches. It also has a very fastonset of action via SC injection or nasal spray administration.However, sumatriptan is contraindicated withmonoamine oxidase inhibitors because it is primarily degradedby hepatic MAO-A. Thus, it may require frequentdosing as a result of its short duration of action to preventmigraine recurrence.
- Sumatriptan
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- US $1.00 / kg
- 2022-11-23
- CAS:103628-46-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10000
- Sumatriptan USP/EP/BP
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- US $1.10 / g
- 2021-06-11
- CAS:103628-46-2
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
- SuMatriptan
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- US $1.00 / g
- 2021-01-06
- CAS:103628-46-4
- Min. Order: 1g
- Purity: Min98% HPLC/GC
- Supply Ability: g/kg/ton Coreychem-Nicole
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103628-46-2
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