134523-00-5 Basic information More..
Product Name:Atorvastatin
Synonyms:Atorvastatin&Ats-5Ats-8Ats-9M4L1;Atrovastitne;(bR,dR)-2-(p-Fluorophenyl)-β,δ-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid;1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βR,δR)-;1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, [R-(R*,R*)]-;Cardyl;[R-(R^<*>^,R^<*>^)]-2-(4-Fluorophenyl)- β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylarnino)carbonyl]-1H.Pyrrole-1- heptanoic acid;(3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxy-enanthic acid
CAS:134523-00-5
MF:C33H35FN2O5
MW:558.65
EINECS:806-698-0
Mol File:134523-00-5.mol
134523-00-5

Use

Atorvastatin, [R-(R*,R*)]-2-(4-fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-lH-pyrrole-1-heptanoic acid(Lipitor), also possesses the heptanoic acid side chain,which is critical for inhibition of HMG-CoA reductase.Although the side chain is less lipophilic than the lactoneform, the high amount of lipophilic substitution causes this agent to have a slightly higher level of CNS penetration thanpravastatin, resulting in a slight increase in CNS side effects.Even so, its CNS profile is much lower than that of lovastatin.Atorvastatin is marketed as a combination therapywith amlodipine under the trade name Norvasc for managementof high cholesterol and high blood pressure.

Atorvastatin manufacturers

  • Atorvastatin
  • US $80.00 / g
  • 2024-02-02
  • CAS:134523-00-5
  • Min. Order: 1g
  • Purity: 98
  • Supply Ability: 20 Kg
  • Atorvastatin
  • US $484.00 / KG
  • 2023-06-15
  • CAS:134523-00-5
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100KG
  • Atorvastatin
  • US $10.00 / Kg/Bag
  • 2021-11-04
  • CAS:134523-00-5
  • Min. Order: 1Kg/Bag
  • Purity: 99%
  • Supply Ability: 20 Tons
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