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trans-Ned-19-d8 Basic information More..
Product Name:trans-Ned-19-d8
Synonyms:(1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-(piperazinyl-d8)]Methyl]-4-Methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;trans-Ned-19-d8
CAS:
MF:C30H30FN4O3
MW:513.5826032
EINECS:
Mol File:Mol File
trans-Ned-19-d8

Use

trans-Ned-19-d8, a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [ 32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells.

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