| | 1432660-47-3 Basic information More.. |
| Product Name: | AGI6780 | | Synonyms: | AGI6780;AGI-6780, >=98%;N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoroMethyl)phenyl)ureido)benzenesulfonaMide;N-Cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-benzenesulfonamide;Benzenesulfonamide, N-cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-;AGI-6780 N-Cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-benzenesulfonamide;N-Cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-benzenesulfonamide AGI-6780;CS-1019 | | CAS: | 1432660-47-3 | | MF: | C21H18F3N3O3S2 | | MW: | 481.51 | | EINECS: | | | Mol File: | 1432660-47-3.mol |  |
Use
AGI-6780 potently reduce (R)-2-hydroxyglutarate (2HG) levels in cell lines ectopically overexpressing IDH2/R140Q with EC50 of 20 nM, with excellent selectivity against other dehydrogenases. AGI-6780 reverses the IDH2/R140Q-induced differentiation block in TF-1 cells, and induces blast differentiation in primary human IDH2/R140Q AML patient samples.
- AGI-6780
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- US $31.00-122.00 / mg
- 2025-10-27
- CAS:1432660-47-3
- Min. Order:
- Purity: 99.70%
- Supply Ability: 10g
- AGI6780
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- US $0.00-0.00 / KG
- 2025-01-03
- CAS:1432660-47-3
- Min. Order: 5g
- Purity: 99% HPLC
- Supply Ability: 2000tons
- AGI6780
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- US $1.00 / KG
- 2019-07-06
- CAS:1432660-47-3
- Min. Order: 1G
- Purity: 98%
- Supply Ability: 100KG
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1432660-47-3
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