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Product Name:Cyclosporin A
Synonyms:ol27-400;s7481f1;sandimmun;Cyclospori;1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane, cyclic peptide deriv.;30-Ethyl-33-(1-hydroxy-2-methyl-hex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-dipropan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone;Cipol N;Neoplanta
CAS:59865-13-3
MF:C62H111N11O12
MW:1202.61
EINECS:611-907-1
Mol File:59865-13-3.mol
59865-13-3

Use

Cyclosporin A is a hydrophobic cyclic peptide isolated from several fungal species including Cylindrocarpon, Fusarium, Trichoderma and Tolypocladium. Cyclosporin A inhibits T-cell activation and has been marketed since 1983 as an immunosuppressant in post-allogeneic organ transplant. Cyclosporin A acts by binding to the protein, cyclophilin (immunophilin), in T-lymphocytes causing inhibition of calcineurin (protein phosphatase 2B). Cyclosporin A reduces transcription of interleukin 2, and inhibits lymphokine production, interleukin release and NO synthesis induced by interleukin 1α, lipopolysaccharides and TNFα.

Cyclosporin A manufacturers

  • Cyclosporin A
  • US $0.00 / kg
  • 2024-04-19
  • CAS:59865-13-3
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 20tons
  • Cyclosporin A
  • US $9.00-70.00 / g
  • 2024-04-19
  • CAS:59865-13-3
  • Min. Order: 10g
  • Purity: 99%
  • Supply Ability: 10 tons
  • Cyclosporin A
  • US $0.00 / kg
  • 2024-04-12
  • CAS:59865-13-3
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 2000ton
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