| | 87638-04-8 Basic information More.. |
| Product Name: | CARUMONAM | | Synonyms: | CARUMONAM;Acetic acid, [[(Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-;Acetic acid, [[[2-[[2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-, [2S-[2α,3α(Z)]]-;AMA 1080;Antibiotic Ro 17-2301;Ro 17-2301;(2S)-2α-(Carbamoyloxymethyl)-3α-[[(Z)-(2-amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-4-oxoazetidine-1-sulfonic acid;[[[(Z)-2-[[(2S)-2α-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3α-yl]amino]-1-(2-aminothiazol-4-yl)-2-oxoethylidene]amino]oxy]acetic acid | | CAS: | 87638-04-8 | | MF: | C12H14N6O10S2 | | MW: | 466.4 | | EINECS: | | | Mol File: | 87638-04-8.mol |  |
Use
A synthetic monobactam with activity against common
pathogenic organisms similar to that of aztreonam. It is resistant
to hydrolysis by the common plasmid and chromosomal
β-lactamases, but it can be hydrolyzed by ESBLs.
It is administered intravenously, achieving a concentration
of c. 78 mg/L after a 20-min infusion of 1 g. The plasma halflife
is 1.7 h and the plasma protein binding 18–28%.
Carumonam is almost entirely eliminated in the glomerular
filtrate, probenecid having no effect on excretion; 96%
of labeled compound is found in the urine, with 3% in the
feces. Between 68% and 91% of the dose appears in the urine
within 24 h.
Side effects and clinical use are similar to those of
aztreonam.
- CaruMonaM
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- US $1.00-1.00 / KG
- 2025-01-03
- CAS:87638-04-8
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 50tons
- CARUMONAM
-
- US $1.00 / g
- 2019-12-26
- CAS:87638-04-8
- Min. Order: 1g
- Purity: ≥98%
- Supply Ability: g/kg/Ton
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87638-04-8
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