51762-05-1 Basic information More..
Product Name:Cefroxadine
Synonyms:cxd;CEFROXADINE;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methoxy-8-oxo-, [6R-[6α,7β(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methoxy-8-oxo-, (6R,7R)-;Oraspor;(6R,7R)-7-[[(2R)-2-Amino-2-(1-cyclohexa-1,4-dienyl)acetyl]amino]-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7R)-7-[[(R)-Amino(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;C12979
CAS:51762-05-1
MF:C16H19N3O5S
MW:365.4
EINECS:257-391-8
Mol File:51762-05-1.mol
51762-05-1

Use

Cefroxadine is closely related to cefradine, the structure differing only by the presence of a methoxy group replacing methyl at the C-3 position. The antimicrobial spectrum is identical to that of cefradine and cefalexin. A dose of 1 g as film-coated tablets produced mean peak plasma levels of 25 mg/L at 1 h. Absorption is depressed and delayed by administration with food. The plasma elimination half-life is 0.8 h, rising to 40 h in end-stage renal failure and falling to 3.4 h during hemodialysis. Around 85% of an oral dose is excreted unchanged in the urine. It is available in Japan.

Cefroxadine manufacturers

  • Cefroxadine
  • US $0.00-0.00 / Kg
  • 2020-05-26
  • CAS:51762-05-1
  • Min. Order: 1KG
  • Purity: 99.0%
  • Supply Ability: 500 MT
  • Cefroxadine
  • US $7.00 / kg
  • 2019-07-06
  • CAS: 51762-05-1
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 100kg
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