1626387-80-1 Basic information More..
Product Name:AZD 3759
Synonyms:AZD 3759;AZD3759;AZD-3759;(2R)-2,4-Dimethyl-1-piperazinecarboxylic acid 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester;HY-18750;azd3579;1-Piperazinecarboxylic acid, 2,4-dimethyl-, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester, (2R)-;1-PIPERAZINECARBOXYLIC ACID, 2,4-DIMETHYL-, 4-[(3-CHLORO-2-FLUOROPHENYL)AMINO]-7-METHOXY-6-QUINAZOLINYL ESTER
CAS:1626387-80-1
MF:C22H23ClFN5O3
MW:459.9
EINECS:1592732-453-0
Mol File:1626387-80-1.mol
1626387-80-1

Use

AZD3759 is an EGFP inhibitor (Epidermal growth factor receptor tyrosine kinase inhibitor) with blood brain barrier (BBB) penetration. It has the potential for the treatment of non-small cell lung cancer (NSCLC), with brain metastases (BM) and leptomengingeal metastases (LM) since this type of cancer often contain a lot of activating mutations of the epidermal growth factor receptor (EGFR). It has excellent capability of penetrating the blood brain barrier to reach the central nervous system.

AZD 3759 manufacturers

  • Zorifertinib
  • US $37.00-83.00 / mg
  • 2025-07-15
  • CAS:1626387-80-1
  • Min. Order:
  • Purity: 99.36%
  • Supply Ability: 10g
  • AZD 3759
  • US $100.00 / kg
  • 2025-07-07
  • CAS:1626387-80-1
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 50000KG/month
  • AZD3759
  • US $0.00 / kg
  • 2025-06-20
  • CAS:1626387-80-1
  • Min. Order: 1kg
  • Purity: 0.99
  • Supply Ability: 20tons
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