1626387-80-1 Basic information More..
Product Name:AZD 3759
Synonyms:AZD 3759;AZD3759;AZD-3759;(2R)-2,4-Dimethyl-1-piperazinecarboxylic acid 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester;HY-18750;azd3579;1-Piperazinecarboxylic acid, 2,4-dimethyl-, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester, (2R)-;1-PIPERAZINECARBOXYLIC ACID, 2,4-DIMETHYL-, 4-[(3-CHLORO-2-FLUOROPHENYL)AMINO]-7-METHOXY-6-QUINAZOLINYL ESTER
CAS:1626387-80-1
MF:C22H23ClFN5O3
MW:459.9
EINECS:1592732-453-0
Mol File:1626387-80-1.mol
1626387-80-1

Use

AZD3759 is an EGFP inhibitor (Epidermal growth factor receptor tyrosine kinase inhibitor) with blood brain barrier (BBB) penetration. It has the potential for the treatment of non-small cell lung cancer (NSCLC), with brain metastases (BM) and leptomengingeal metastases (LM) since this type of cancer often contain a lot of activating mutations of the epidermal growth factor receptor (EGFR). It has excellent capability of penetrating the blood brain barrier to reach the central nervous system.

Lastest Price from AZD 3759 manufacturers

  • AZD 3759
  • US $100.00 / ASSAYS
  • 2021-12-06
  • CAS:1626387-80-1
  • Min. Order: 1ASSAYS
  • Purity: 99.9%
  • Supply Ability: 800kgs/month
  • AZD3759
  • US $0.00 / KG
  • 2021-11-15
  • CAS:1626387-80-1
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 200000pcs
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