152121-30-7 Basic information More..
Product Name:SB 202190
Synonyms:4-[4-(4-FLUOROPHENYL)-5-(4-PYRIDINYL)-1H-IMIDAZOL-2-YL]PHENOL;4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE;4-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-2H-imidazol-2-yl)phenol;Aids110355;Aids-110355;Phenol, 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-;SB 202190;SB 202190,4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole
CAS:152121-30-7
MF:C20H14FN3O
MW:331.34
EINECS:
Mol File:152121-30-7.mol
152121-30-7

Use

SB 202190 is a DFG inhibitor used in the treatment of colorectal cancer. It is a highly selective, potent inhibitor of p38 MAP kinase. SB-202190 is able to promote proliferation of C6 cells in lower c oncentration but induced apoptosis in higher levels. Studies show that SB202190 can protect neural function from ischemia/reperfusion injury and regulate the activation of Bcl-2 and Bax protein after ischemia/reperfusion in rat.

SB 202190 manufacturers

  • SB 202190
  • US $1.10 / g
  • 2021-09-27
  • CAS:152121-30-7
  • Min. Order: 1g
  • Purity: 99.00%
  • Supply Ability: 100 Tons Min
  • SB 202190
  • US $1.00 / KG
  • 2019-07-06
  • CAS:152121-30-7
  • Min. Order: 1KG
  • Purity: 98-100%
  • Supply Ability: 1000kg
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Products Intro: Product Name:4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-dihydroimidazol-2-ylidene]cyclohexa-2,5-dien-1-one
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