| | 128794-94-5 Basic information More.. |
| Product Name: | Mycophenolate mofetil | | Synonyms: | Mofetil mycophenolate;4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E);Nsc724229;Mycophenolate mofetil;6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoicacid2-(4-morpholinyl)ethylester;Mycophenolate Mofetil (200 mg);(E)-2-Morpholinoethyl 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-meth;2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate | | CAS: | 128794-94-5 | | MF: | C23H31NO7 | | MW: | 433.49 | | EINECS: | | | Mol File: | 128794-94-5.mol |  |
Use
Mycophenolate mofetil was launched in 1995 in the U.S.A., its first market
worldwide, for the prevention of acute kidney transplant rejection in conjunction with
other immunosuppressive therapy and to treat refractory acute kidney graft rejection.
With improved oral absorption and bioavailability, mycophenolate mofetil is a prodrug of
mycophenolic acid (MPA), a fermentation product of several Penicillium species. MPA
is a selective, reversible, non-competitive inhibitor of inosinate dehydrogenase and
guanylate synthetase. It inhibits the de now pathway of purine biosynthesis. MPA
was found to have more potent antiproliferative effects on T and B lymphocytes than
other cell types. Compared with other immunosuppressants, mycophenolate mofetil is
reportedly superior due to its unique mechanism of action and excellent safety profile
for long term use. Mycophenolate mofetil is being investigated clinically in the
treatment of heart and liver transplantation rejection, asthma, in preventing coronary
artery restenosis, and in treating rheumatoid arthritis.
- Mycophenolate mofetil
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- US $0.00 / KG
- 2024-03-12
- CAS:128794-94-5
- Min. Order: 1KG
- Purity: 98% HPLC
- Supply Ability: 200kg
- Mycophenolate mofetil
-
- US $0.00 / mg
- 2023-11-27
- CAS:128794-94-5
- Min. Order: 100mg
- Purity: 99%
- Supply Ability: 50kg
- Mycophenolate Mofetil
-
- US $0.00 / kg
- 2021-07-06
- CAS:128794-94-5
- Min. Order: 1kg
- Purity: 98
- Supply Ability: 10MT
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128794-94-5
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