| | 29070-92-6 Basic information More.. |
| Product Name: | Pachymic acid | | Synonyms: | 3-ACETYLTUMULOSIC ACID;PACHYMIC ACID;(3b,16a)-3-(Acetyloxy)-16-hydroxy-24-methylenelanost-8-en-21-oic acid;24-methylene-,(3β,16α)-;3-O-Acetyltumulosic acid;Lanost-8-en-21-oic acid, 3-(acetyloxy)-16-hydroxy-;3β-Acetyloxy-16α-hydroxy-24-methylenelanost-8-en-21-oic acid;Ccris 7792 | | CAS: | 29070-92-6 | | MF: | C33H52O5 | | MW: | 528.76 | | EINECS: | | | Mol File: | 29070-92-6.mol |  |
Use
Pachymic acid (PA) is a natural triterpenoid known to inhibit the phospholipase A2 (PLA(2)) family of arachidonic acid (AA)-producing enzymes, PA-treatment decreases bad phosphorylation, increases Bcl-2 phosphorylation, and activates caspases-9 and -3, it also decreases the expression and activation of proteins within the AKT signal pathway. suggests that PA initiates apoptosis through mitochondria dysfunction and influences apoptosis by reducing prostaglandin.Pachymic acid can exhibit antiinflammatory and anticancer properties, it can inhibit cell growth and modulate arachidonic acid metabolism in nonsmall cell lung cancer A549 cells by its inhibition of MAPKs and NF-kappaB signaling pathways; it can impair breast cancer cell invasion by suppressing nuclear factor-κB-dependent matrix metalloproteinase-9 expression.
- Pachymic acid
-
- US $0.00-0.00 / kg
- 2024-04-24
- CAS:29070-92-6
- Min. Order: 0.10000000149011612kg
- Purity: ≥99%
- Supply Ability: 20tons
- Pachymic acid
-
- US $0.00 / MG
- 2024-04-23
- CAS:29070-92-6
- Min. Order: 20MG
- Purity: ≥98% HPLC
- Supply Ability: 100KG
- Pachymic acid
-
- US $0.00 / MG
- 2024-04-23
- CAS:29070-92-6
- Min. Order: 20MG
- Purity: ≥98% HPLC
- Supply Ability: 100KG
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29070-92-6
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