476-28-8 Basic information More..
Product Name:LYCORINE
Synonyms:2-beta-diol,3,3-alpha-didehydro-lycoran-1-alph;Amaryline;amarylline;Belamarine;galanthan-1,2-diol,3,12-didehydro-9,10-(methylenebis(oxy))-,(1-alpha,2-beta;galanthidine;narcissine;LYCORINE HPLC 98+%
CAS:476-28-8
MF:C16H17NO4
MW:287.31
EINECS:207-503-6
Mol File:476-28-8.mol
476-28-8

Use

Lycorine is an analgesic, more so than aspirin, and a hypotensive, as are caranine and galanthine . The analgesic activity exhibited by the Amaryllidaceae alkaloids is attributed to their resemblance to the morphine and codeine skeletons. Lycorine also has antiarrhythmic action, and lycorine hydrochloride is a strong broncholytic. In fact, lycorine shows a relaxant effect on an isolated epinephrine-precontracted pulmonary artery and increases contractility and the rate of an isolated perfused heart. These effects are mediated by stimulation of b-adrenergic receptors.Lycorine also has a strong inhibitory effect on parasite (Encephalitozoon intestinalis) development and antifungal activity against Candida albicans. Additionally, lycorine has antifeedant, antimalarial, emetic, anti-inflammatory, antiplatelet , as well as antifertility activities. Galanthine, in turn, shows mild in vitro activity against Tripanosoma brucei rhodesiense and Plasmodium falciparum.

LYCORINE manufacturers

  • LYCORINE USP/EP/BP
  • US $1.10 / g
  • 2021-06-18
  • CAS:476-28-8
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons Min
  • LYCORINE
  • US $2.00 / KG
  • 2019-07-06
  • CAS:476-28-8
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 10000kg
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