288250-47-5 Basic information More..
Product Name:Y320
Synonyms:Y320;1-(4-CHLOROPHENYL)-N-(3-CYANO-4-(4-MORPHOLINOPIPERIDIN-1-YL)PHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE;1-(4-Chlorophenyl)-N-[3-cyano-4-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-5-methyl-1H-pyrazole-4-carboxamide;1-(4-Chlorophenyl)-N-(3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl)-5-methyl-1H-pyrazole-4-car;1-(4-Chlorophenyl)-N-[3-cyano-4-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-5-methyl-1H-pyrazole-4-carboxamide Y320;Y320 1-(4-Chlorophenyl)-N-[3-cyano-4-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-5-methyl-1H-pyrazole-4-carboxamide;Y-320, >=98%;1-(4-Chlorophenyl)-N-(3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl)-5-methyl-1H-pyrazole-4-carboxami
CAS:288250-47-5
MF:C27H29ClN6O2
MW:505.01
EINECS:200-256-5
Mol File:288250-47-5.mol
288250-47-5

Use

Y-320 (0.3-3 mg/kg p.o.) ameliorates collagen-induced arthritis (CIA) in Mice with a reduction of IL-17 mRNA in arthritic joints, and also shows therapeutic effects on CIA in cynomolgus monkeys. Moreover, Y-320 shows a synergistic effect in combination with anti-TNF-α mAb on chronic-progressing CIA in mice.

Y320 manufacturers

  • Y320
  • US $5.00 / KG
  • 2019-09-04
  • CAS:288250-47-5
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 1ton
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